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Research Article
Al-Said A Haffor* and Khaldoon Al-Jernia View abstract
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Background: The lungs clearance index (LCI) is used to assess the efficiency of ventilation distribution homogeneity among the bronchial tree. Purpose: The purpose of this study was to compare LCI with the standard pulmonary functions tests (PFT) as well as some selected gas exchange measures in three groups; healthy individuals, chronic obstructive pulmonary (COPD) and chronic restrictive pulmonary diseases (CRPD). Methods: LCI was determined from the slope of phase-III of the nitrogen washout curve during single breath (SBN2W). PFT and gas exchange measures were determined using metabolic cart, Vmax29. Results: One Way analysis (ANOVA) showed significant (p<0.05) main effects of group membership (Healthy vs. COPD Vs. RLD) on LCI and PFT forced breathing measures (FEV1, FVC, FEV1/FVC ratio). In addition, there was a significant main effe..... ReadMore -
Case Report
Mohammad A Hye* and Siddhartha Shankar Dutta View abstract
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Down syndrome (DS) is the most common congenital abnormality affecting numerous organs and is associated with an increased incidence of many cutaneous diseases. DS is an extensively researched condition but its associated cutaneous diseases are not well studied. Only a small numbers of case reports on lichenoid diseases associated with DS are reported in literature. So far, we know, there is no report published on classical lichen planus with DS until now. We reported a case of lichen planus in an adult patient of Down syndrome. We treated the patient with systemic acitretin. Patient has been observed for last three years. A good result was observed without any complication or relapse.Down syndrome (DS), also known as trisomy 21, is an autosomal chromosomal disorder caused by the presence of al..... ReadMore
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Case Report
Soldatou Alexandra*, Syggelou Angeliki, Stamataki Sofia, Taprantzi-Potamianou Polyxeni and Lydia Kossiva View abstract
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A 14-year-old female presented with acute onset of cough, fever and chest pain. She had a one-month history of cough treated with broad-spectrum antibiotics and bronchodilators. Several hours prior to admission, she developed fever up to 39.5 oC with chills and chest pain with radiation to her back on deep inspiration. Her past medical and family histories were unremarkable. She was a well-developed adolescent female in no acute distress, 98% oxygen saturation in room air and normal breath sounds on auscultation. Laboratory studies revealed leukocytosis (WBC, 16.6 x 103/μl) with a predominance of neutrophils (80%), elevated C-reactive protein (CRP, 89 mg/L) and erythrocyte sedimentation rate (ESR, 75mm). A chest radiograph revealed left upper lobe atelectasis and infiltrate, and a small effusio..... ReadMore
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Case Report
Maouni Safae*, El Anzi Ouiam, Sialiti Sanae, Zenati Kaoutar, Meziane Mariam, Benzekri Leila, Nadia Ismaili, Senouci Karima and Hassam Badredine View abstract
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Subcutaneous Panniculitis-like T-lymphoma (SPTL) is a rare non-epidermotropic cutaneous T cell lymphoma, which perform 1% of all non-Hodgkin’s lymphomas. The lesions are usually localized in the upper limbs and the trunk. the localization on the cheeks is unusual. The diagnosis of SPTCL depends on the pathologic examination of skin biopsy, but the manifestations of SPTCL are varied and mimic autoimmune disorders. We report a case of a subcutaneous panniculitis-like t-cell lymphoma with an unusual localization in the cheek, mimicking a lupus erythematosus panniculitis, evolving since 2 years in a 40-year-old woman...... ReadMore
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Case Report
El Anzi Ouiam*, Maouni Safae, Sqalli Asmae and Hassam Badredine View abstract
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Lichen amyloidosis (LA) is the most common form of primary cutaneous amyloidosis. It�s a very pruritic hyperkeratotic and coalescent papules usually localized on the anterior tibiae. The diagnostic is clinical, dermoscopy reveals two major dermoscopic patterns characteristic of LA, namely, �central hub� and �scar-like�...... ReadMore
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Case Report
Maouni Safae View abstract
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Sarcoidosis is a granulomatous systemic disease of undetermined origin. Its dermatological manifestations are present in 25% of cases and they are very polymorphic. Nail abnormalities are unusual in sarcoidosis and are often an indication of systemic involvement. Dermoscopy of the nail may be very useful in some isolated cases and can guide us to the right diagnosis. We report a rare case of systemic sarcoidosis presenting as nail dystrophy with painful phalanges and underlying bony cysts, treated successfully by oral corticosteroid with good evolution..... ReadMore
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Review Article
Amal O Al-Balbeesi View abstract
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Ocular manifestations of rosacea are commonly nonspecific and variable. The etiology of the inflammation is not fully known and there is no definite diagnostic test for the disease. We often under diagnose the disease, despite the potential for serious sightthreatening sequelae. When evaluating patients with rosacea, dermatologists and family physicians should obtain a careful history of eye complaints and examine the eyelid margins thoroughly. Patients with moderate-to-severe ocular findings will benefit from evaluation by an ophthalmologist. Controlling symptoms and preventing potential risk of blindness should be the aim of early diagnosis and prompt intervention. The mainstay of treatment is good lid hygiene, topical metronidazole, topical azithromycin eye drops, topical cyclosporine, and oral tetracycline. The aim of this review is t..... ReadMore
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Research Article
Akhilesh Gupta* View abstract
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Life-threatening illness occurs due to Aspergillus species cause a spectrum of disease ranging from airway colonization. In case of respiratory tract, aspergilloma is the most common form of pulmonary involvement, which is usually accompanied by preexisting lung disease finally architectural abnormalities most commonly stem from tuberculosis, although other associated conditions, such as sarcoidosis, bronchiectasis, and neoplasm, have been documented. Methodology: The present work comprised of synthesis and cyclization of substituted benzothiazole nucleus by reaction of substituted aniline with potassium thiocynate in presence of bromine in glacial acetic acid and ammonia under temperature control. Substituted benzothiazole then condensed with 2 (3 or 4)-nitrobenzoylchloride acid in presence of dry pyridine and acetone to get substituted ..... ReadMore
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Research Article
Sudhir Sawarkar*, Vinay Deshmukh and Sankar Jayaganesh View abstract
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The human scalp is susceptible to microbial build-up if not thoroughly and frequently washed with the appropriate cleansing agents such as shampoos. Natural oils are presented in our scalp and it called as a sebum and it is a fuel/food for the dandruff-causing microbe. Malassezia feeds off these oils, breaking it down into by products, including oleic acid; formation of oleic acid is a starting/kick point of dandruff. Approximately 50% people in the world sensitive to the oleic acid and affected by the dandruff. Overall clinical study results revealed that usage of tested anti-dandruff shampoo is effective and significantly reduce the dandruff fungi in scalp. Efficacy was analyzed with changes in the intensity of hair fall over 6 weeks from baseline to treatment visits using Visual Analogue Scale (VAS). The average res..... ReadMore
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Review Article
Irikefe Paul Obiebi View abstract
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Background: Documented evidence confirms that inhalation of toxic substances emitted during charcoal production is associated with lung function deficits and respiratory symptoms nonetheless; other factors could also give rise to the similar respiratory disorders or problems. This study was designed to ascertain the influence other impinging factors wield on the respiratory symptoms and lung function deficits among workers at wood-burning earth kilns. Methodology: This was a cross-sectional analytic study conducted among workers exposed to wood smoke from wood-burning earth kilns in Southern Nigeria. A comprehensive sampling of all workers who willing consented to participate in this study was done since the workers were few. A modified Medical Research Council Questionnaire as well as a portable spirometer was the study instrument. Data..... ReadMore
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Review Article
Sarvath Ali View abstract
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Background Globally, including the United States, cigarette smoking is the single most important cause of premature death, even though it is preventable. The prevalence of smoking is high, although some resources have been dedicated to this problem. A variety of interventions have been tried on smoking prevention. From the public health perspective, it is the biggest concern. As there are numerous health benefits of smoking cessation, most individuals who smoke express a desire to quit. Studies show that most smokers in the United States and the United Kingdom report that they want to stop or intend to leave smoking at some point in life Hyland [1]. A multitude of non-pharmacological and pharmacological interventions now exist to aid smokers in cessation. Objectives To bring awareness among public and policy makers. To provide evidence..... ReadMore
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Image Article
Alireza Heidari View abstract
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In the current study, we have experimentally and comparatively investigated and compared malignant human cancer cells and tissues such as Bladder Cancer, Breast Cancer, Colorectal Cancer, Endometrial Cancer, Kidney Cancer, Leukemia, Liver, Lung Cancer, Melanoma, Non-Hodgkin Lymphoma, Pancreatic Cancer, Prostate Cancer, Thyroid Cancer and Non-Melanoma Skin Cancer before and after irradiating of synchrotron radiation for proton beam therapy using Correlation Spectroscopy (COSY), Exclusive Correlation Spectroscopy (ECOSY), Total Correlation Spectroscopy (TOCSY), Incredible Natural-Abundance Double-Quantum Transfer Experiment (INADEQUATE), Heteronuclear Single-Quantum Correlation Spectroscopy (HSQC), Heteronuclear Multiple-Bond Correlation Spectroscopy (HMBC), Nuclear Over hauser Effect Spectroscopy (NOESY) and Rotating Frame Nuclear Over hau..... ReadMore
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Review Article
Jacques Lukenze Tamuzi View abstract
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Background: Epidemiologic data on atopic diseases are scared. Different studies have shown that the burden of atopic diseases is varying in space and time. Several factors are impacting on epidemiology of atopic in children. Among them, MMR vaccination has been a topic of divergences. Objective: To stablish whether the MMR vaccination may influence the risk of atopic diseases in children. Methods: We conducted electronic search terms included MESH or key words with “Atopic diseases” and “MMR vaccination” and “Children”. Databases for peer-reviewed articles included Pub Med, CENTRAL, Scopus and CINAHL Plus. Additionally, Grey literature was obtained from Google and WHO database. Main results: Among 304 potentially relevant articles identified, 8 peer-reviewed articles met the inclusion criteria. Due to the lack of standardized..... ReadMore
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