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Durairaj Dhanapal*, Siwala Mundia and S Nagaraj

DOI : 10.32474/RRHOAJ.2022.07.000272

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High Heel and stiletto are very popular and fashionable among women especially in today, many women wear high heeled as a daily basis to increase the femininity and attractiveness, many these high heels remain popular despite the negative effects to the human foots...... ReadMore

Durairaj Dhanapal*, Siwala Mundia and S Nagaraj

DOI : 10.32474/RRHOAJ.2022.07.000271

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Footwear are one of the consumer materials and an engineering product, Globally China is the largest footwear production country, and India is the second largest footwear production after China for approximately 9% of the global annual production of 22 million pairs. The footwear production industry having many more working process and machinery utilization that sector is fragmented and close to 75% footwear production in unorganized sector including small scale and medium enterprises...... ReadMore

Friedrich Mehrhoff and Marlon Becker*

DOI : 10.32474/RRHOAJ.2022.07.000270

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The following guidelines are based on an international study of DGUV in 2019, which was commissioned for the German Ministry of Labor and Social Affairs. These golden rules are dedicated to enterprises in the private and first labor market regardless of size and branch of the companies...... ReadMore

Francesco Natale*, Riccardo Molinari, Simona Covino, Paolo Golino and Giovanni Cimmino

DOI : 10.32474/RRHOAJ.2022.07.000269

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In 1842 Dr. Christian Andreas Doppler published his work“Über das farbige Licht der Doppelsterne und einiger andererGestirne des Himmels”. In his treatise Dr. Christian Doppler analyses the color of light emitted by binary star systems. A binarystar system is composed of 2 stars orbiting around each other, bound by gravitational forces. A stationary star has a whitishyellow color; conversely, in a Binary star system the star moving away from the observer emits a reddish hue light with a longer wavelength, shifting towards the infrared spectrum (redshift), while an approaching star emits a blue hue light, with a shortened wavelength, shifting toward the ultraviolet spectrum (blue-shift) [1]. With the experiments of Dr. Buys-Ballot in the early 1900s, the principles of “Doppler effect” were investigated in relation to soundwaves, l..... ReadMore

Kowalski GJ*

DOI : 10.32474/RRHOAJ.2022.07.000268

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Background: Primary hyperparathyroidism (pHPT) is caused by benign and malignant conditions. Most commonly by typical adenoma/single gland disease (PA) - this is 80-85% cases of pHPT. Parathyroid hyperplasia or multiple gland disease accounts for 10-15% of cases of PHPT. Atypical parathyroid adenoma (APA) and carcinoma (PC) - very rare conditions -are both responsible for pHPT in approximately 0,5 - 1,5% of cases. Objectives: To estimate occurrence of atypical parathyroid adenoma, parathyroid carcinoma and parathyroid hyperplasia along with characterize them based on their etiology, clinical presentation, diagnosis and treatment. Methods: We performed a retrospective study and enrolled 1,019 patients with primary hyperparathyroidism undergoing parathyroidectomy at academic Department of General and Endocrine Surgery between 1983 and 2..... ReadMore

Raja Nandyal*, Michele Coleman and Susan Bedwell DNP

DOI : 10.32474/RRHOAJ.2022.07.000267

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In 1997, the American Academy of Pediatrics (AAP) recommended that the sound levels be limited to less than 45 dB in a Neonatal Intensive Care Unit (NICU). Follow-up studies of growing premature infants show high incidence of neurodevelopmental problems, including hearing loss. This is an observational study to assess the sound levels that a neonate can be potentially exposed to during the transport in a closed incubator from the delivery room to NICU. Sound levels were measured using a dosimeter. A continuous recording of sound decibels was made with the time stamped, at nine predetermined specific points during the transit. In addition to preparatory runs, sound levels for ten separate consecutive runs were measured to account for the variations in the extraneous environmental noise. All ten runs h..... ReadMore

Jürgen Bünger*, Eike Marek, Vera van Kampen and Thomas Brüning

DOI : 10.32474/RRHOAJ.2022.07.000266

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At workplaces, many additional conditions and influences must be considered when choosing adequate personal protection equipment, including masks to protect from SARS-CoV-2 infection and transmission to other workmates. Conditions like type,proximity and duration of contact with colleagues, duration of mask wear, virus load, heat, humidity must be included for the risk analysis and decision if a mask is needed and if yes, what kind of mask is the best choice. A good scientific knowledge on the efficiency and burden of protection against SARS-CoV-2 by wearing masks is useful as an additional fundamental prerequisite for this decision. Depending on the type of mask, respiratory masks can be effective for both self-protection and protection of others (Asadi et al. [1], Chu et al. [2], Leung et al. [3], Liang et al. [4]). ..... ReadMore

Housam Yousef Almadani*, Mohammed Abdulbasit Almelibari, Mohamed I El hefnawy, Banan Alaied, Talal H Albishri, Samy Marouf, Ebtihaj Jamil Abdulqadim, Antoine Amaury Lachaud, Rita Dittmer and Pierre Alain Menoud

DOI : 10.32474/RRHOAJ.2022.07.000265

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Thrombotic thrombocytopenic purpura (TTP) is a life-threatening form of thrombotic microangiopathy (TMA) characterized by recurrent episodes of thrombocytopenia and microangiopathic hemolytic anemia (MAHA), sometimes associated with ischemic damage of the brain and kidneys. Congenital TTP (cTTP), also known as Upshaw–Schulman syndrome, is a rare disease caused by compound heterozygous, or more rarely, homozygous mutations in the gene encoding the von Willebrand factor (VWF) cleaving protease, ADAMTS13 (a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13). The disease course in cTTP is variable and genotype-phenotype correlations are complex. In this report we describe a case of cTTP in a patient from Saudi Arabia caused by a novel homozygous mutation (c.2882delC; p. Cys962Alafs*3) predicted to result in tru..... ReadMore

Teresa A. Simon*, Gowri Priya Harikrishnan, H Joachim Deeg, Tzuyung D Kou, John H Simon and Andres Gomez Caminero

DOI : 10.32474/RRHOAJ.2022.07.000264

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Background: Risk-benefit assessment data for myelodysplastic syndrome (MDS) treatment are scarce. We characterized baseline factors and clinical course data in patients with MDS who progressed to acute myeloid leukemia (AML) or underwent allogeneic hematopoietic stem cell transplantation (allo-HSCT) in a real-world observational study using demographic, disease, and treatment claims data from a large US administrative healthcare database. Methods: The study period was from July 1, 2002, to June 30, 2018. The incidence rates (per 1000 patients/year) of progression to AML and undergoing allo-HSCT were evaluated...... ReadMore

Sorush Niknamian*, Somayeh Zaminpira

DOI : 10.32474/RRHOAJ.2022.07.000263

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Objective: The aim of this research is to introduce new method of the treatment/control of Omicron Virus and answer some major questions regarding the cure of COVID-19 and the new type: Omicron. Background: We have selected 24 patients (12 females plus 12 males) aged from 15-64 years of old contaminated severe Omicron virus and used the novel methods on the treatment of these patients. Introduction: The Omicron variant (B.1.1.529) is a variant of SARS-CoV-2 which was first reported to the World Health Organization (WHO) from South Africa on 24 November 2021. Omicron multiplies around 70 times faster than the Delta variant in the bronchi, but some evidence suggests that it is less severe than previous strains, specifically compared to the Delta variant. Omicron might be less able to penetrate deep lung tissu..... ReadMore

Mohammad Hossein Sharifi*, Masood Karimi, Vahid Keshtkar, Hossein Molavi Vardanjani and Somayeh Zarei

DOI : 10.32474/RRHOAJ.2022.07.000262

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adolescent obesity is one of the most serious public health problems. The most common obesity treatments include built-in of diet, exercise, and behavior therapy has not great success in adolescent obesity treatment. Thus, clinicians should take to effective and practical interventions to manage the adolescent obesity. There are multi-approaches in obesity treatment, but most available forms of treatment are complex, not specific for adolescent age group, and ineffective in long term. Moreover, there had had less attention to psychological issues such as, emotional problems, cognitive intervention, motivation interview, self-monitoring, self- help and body image in pediatric obesity management. On the other side, best practical approach to the treatment of adolescent obesity and maintenance is still under controversy. With ref..... ReadMore

Vladimir Zaichick*

DOI : 10.32474/RRHOAJ.2022.07.000261

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Thyroid benign nodules (TBNs) are the most common diseases of this endocrine gland and are common worldwide. The etiology and pathogenesis of TBNs must be considered as multifactorial. The present study was performed to clarify the role of some chemical elements (ChEs) in the etiology of these thyroid disorders. With this aim thyroid tissue levels of aluminum (Al), boron (B), barium (Ba), calcium (Ca), chlorine (Cl), coper (Cu), iron (Fe), I, potassium (K), lithium (Li), magnesium (Mg), manganese (Mn), sodium (Na), phosphorus (P), sulfur (S), silicon (Si), strontium (Sr), vanadium (V), and zinc (Zn) were prospectively evaluated in nodular tissue and tissue adjacent to nodules of 79 patients with TBNs. Measurements were performed using a combination of..... ReadMore

Adaeze Oguegbu*

DOI : 10.32474/RRHOAJ.2022.07.000260

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Health as the totality of a person(s) state of mind, physic and social wellbeing is prioritized all around the world. This is imperative because health determines ones abilities and capabilities which reflect in the input one could make in their environment for improved productivity. The nation with healthy individuals stands to excel in national growth and development which affirms the maxim health is wealth. A healthy nation is a wealthy nation thus to achieve any kind of development in any sector, it has to attained through healthy individuals. Sequel to this, sustainable developmental goals have to be accomplished when the citizens of the country are sound physically, socially and psychologically. In the absence of good health of the citizens, the national aims and objective..... ReadMore

Mustafaev IA*, Bogdanova AV, Tishkov AV, Allakhverdieva LI and Titova ON

DOI : 10.32474/RRHOAJ.2022.07.000259

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Cannabis sativa L., commonly known as hemp, is a herbaceous plant belonging to the family Cannabaceae. Although its exact origin is not known due to its long history of cultivation, it is of Central Asian origin according to a common view (Farinon et al. [1]). Its cultivation is thought to have begun in China in 2800 BC. It spread from China to India and Iran and then to Europe. In the Middle Ages, hemp was grown extensively in Europe for use as a fiber, and its seeds were cooked with other grains (Apostol [2]). Hemp was an important crop in many European countries, including England, France, the Netherlands, Germany, Spain, and Italy during the Middle Ages and until the end of the sailing ship period (Carus and Sarmento [3]). In the past, it was traditionally produced as a fiber crop for textile and rope production. But since the first h..... ReadMore

Elif Adanur Uzunlar* and Bahittin Kahveci

DOI : 10.32474/RRHOAJ.2022.07.000258

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Cannabis sativa L., commonly known as hemp, is a herbaceous plant belonging to the family Cannabaceae. Although its exact origin is not known due to its long history of cultivation, it is of Central Asian origin according to a common view (Farinon et al. [1]). Its cultivation is thought to have begun in China in 2800 BC. It spread from China to India and Iran and then to Europe. In the Middle Ages, hemp was grown extensively in Europe for use as a fiber, and its seeds were cooked with other grains (Apostol [2]). Hemp was an important crop in many European countries, including England, France, the Netherlands, Germany, Spain, and Italy during the Middle Ages and until the end of the sailing ship period (Carus and Sarmento [3]). In the past, it was traditionally produced as a fiber crop for textile and rope production. But since the first h..... ReadMore

Amit Gosar, Shivaji Jadhav, Mithun Gharat*, Mahesh Patil and Dyandev Kadu

DOI : 10.32474/RRHOAJ.2021.07.000257

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Clopidogrel, sold as the brand name Plavix among others. is an antiplatelet medication that is used to reduce the risk of heart disease and stroke in those at high risk [1]. It is also used together with aspirin in heart attacks and following the placement of a coronary arterystent. It is taken by mouth. Onset of effects is about 2 hours and lasts for 5 days [2]. Clopidogrel is in thethienopyridine-class of antiplatelets [3]. It works by irreversibly inhibiting a receptor called P2Y12 on platelets [4,5]. Clopidogrel hydrogen sulfate is a pharmaceutical Active Ingredient with a novel mechanism of action for the reduction of atherosclerotic events. There are only two crystalline forms Clopidogrel hydrogen sulfate I and Clopidogrel hydrogen sulfate II among the six known polymorphs of Clopidogrel hydrogen sulfate have therapeutic activity. T..... ReadMore

Xia Jiang and Bin Zhao*

DOI : 10.32474/RRHOAJ.2021.07.000256

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Breast cancer is one of the most lethal cancers, estrogen receptor α Subtype (ERα) is an important target. The compounds that able to fight ERα active may be candidates for treatment of breast cancer. According to ERα activity, pharmacokinetic properties and safety of the compounds identified 15 biological activity descriptors. In this paper, 15 biological activity descriptors were verified according to the gradient optimization algorithm based on neural network. The research shows that these 15 biological activity descriptors can not only predict ERα with low error, can also predict the pharmacokinetic properties and safety with an accuracy more than 90%. Therefore, these biological activity descriptors has great medical research value...... ReadMore

Shaltout FA, Heikal GI and Ghanem AM*

DOI : 10.32474/RRHOAJ.2021.07.000255

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Chicken meat and meat products production in developing countries plays an essential role in supporting food security and poultry meat demands Wong et al. [1]. Contamination of meat products with molds can be occur during different preparation stages during slaughtering under bad hygienic conditions using contaminated water or by adding contaminated spices with mold spores or during packing, handling, transportation and storage Khalalfalla et al. [2]. Contamination of meat with Aspergillus species, especially Flavi section, is one of the most hazardous microbial contamination as the majority of Aspergillus species are able to aflatoxins production that can cause diseases associated with aflatoxin poisoning and carcinogenic effects Leggieri et al. [3]. Acute aflatoxin poisoning may lead to death as was recorded in Kenya in 2004 Probst et a..... ReadMore

Olga Caridad León González, Pedro Rolando López Rodríguez*, Lais Angélica Ceruto Ortiz, Jorge Agustín Satorre Rocha, Eduardo García Castillo,Luis Marrero Quiala

DOI : 10.32474/RRHOAJ.2021.07.000254

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Since the concept of endoscopic inguinal hernia repair was first described by Ger in 1982, endoscopic techniques have been modified; It was a time when failures and complications - coupled with high cost - outweighed initial enthusiasm [1]. Laparoscopic hernioplasty (LH) has gained popularity in the last decade and numerous controlled studies appear in the literature comparing laparoscopic techniques with conventional ones [2]. In recent years, HL, despite being one of the most controversial laparoscopic procedures, has established itself as a therapeutic option to consider. The advantages of this method are demonstrated in bilateral, recurrent hernias and in the labor-active subject, who requires early return to work [3]. Method Between January 2013 and December 2020, a prospective, descriptive, longitudinal-cut study was carried out in ..... ReadMore

Oguegbu Kramarsky V*, Trusov YV and Faizulina of NI

DOI : 10.32474/RRHOAJ.2021.07.000253

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Postmature pregnancy is the thorny problem of modern obstetrics. Actuality of her is conditioned by high perinatal morbidity and death rate, and also by the large number of complications in luing-ins and delivery operations. Frequency of postmature pregnancy in a population makes from 8 to 10% and does not have a tendency to the decline Neonatal morbidity at postmature pregnancy arrives at 29%, and mortinatality - 19%, that higher, than at the worn pregnancy [1, 2]. It is related to subzero stability of fruit to the hypoxia because of greater maturity of cerebrum and reduction of receipt to him oxygen from morphological changes in a placenta. Prolonged pregnancy lasts more than 287 days, is not accompanied by fetal suffering, and ends with the birth of a healthy child without signs of overmaturity [3, 4]. One of the adaptive mechanisms du..... ReadMore