Rhinal Cortices Connecting the Papez and Yakovlev Circuits: An Integrated Viewpoint Through MRI Epidemiology to Animal Experiment for Better Understanding Clinical Features of Alzheimer Disease and Vascular Dementia Volume 4 - Issue 4

Kenichi Meguro*

• Geriatric Behavioral Neurology, Tohoku University New Industry Creation Hatchery Center, Tohoku University, Tohoku University Graduate School of Medicine, Japan

Received: September 28, 2020;   Published: October 07, 2020

Corresponding author: Kenichi Meguro, Project Leader and Professor, Geriatric Behavioral Neurology Project, Tohoku University New Industry Creation Hatchery Center, Cyclotron Radioisotope Center, Tohoku University, Tohoku University Graduate School of Medicine, Seiyo-machi, IDAC, Aoba-ku, 980-8575 Sendai, Japan

DOI: 10.32474/OJNBD.2020.04.000193

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Abstract

I herein present a unique statement, not focusing on the specific area but present an integrated viewpoint through MRI epidemiology to animal experiment. The aim is to provide a perspective for better understanding clinical features of Alzheimer disease (AD) and vascular dementia (VaD). It is well known that AD and VaD are two major dementing diseases [1,2], and the clinical features are different; grossly, AD shows disintegrated emotion and cognitive function, and VaD shows apathy. First, I will present two typical VaD cases.

Introduction| Case Reports of VaD with Thalamic Infarctions| MRI Epidemiology Disclosed an Importance of Entorhinal Cortex| Functional Neuroimaging and an Animal Experiment| Functional Neuronal Networks for Better Understanding of AD and VaD| References|