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Saad Kadhom Hamid Al Zawi*

DOI : 10.32474/LOJMS.2022.06.000232

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Understanding the effects of anesthesia and the techniques used in eye surgery are very important to providing perioperative anesthesia care. This study aimed to identify the type of anesthesia was used of ophthalmic surgery and comparison between them during the study period. A cross-sectional study was conducted in all the hospital which included the eyes clinic in Baghdad. All the cases admitted from the 1st of January 2020 up to the end of December 2020 were enrolled in this study. We included all the cases of various reasons. Semi-structured questionnaire was used to collect the information on them. The sample size was 27,010 cases. Data was described by using the descriptive statistics such as frequency, percentage, Fisher chi-square, and p. value. STATA version 14 statistical package was used to analyze the data. There .....ReadMore

Revanth Katamareddy, Saraswathi Lakkasani*, Gowthami Sai Kogilathota Jagirdhar, Scott Digiacomo and Yatinder Bains

DOI : 10.32474/LOJMS.2022.06.000231

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Turner’s syndrome is a genetic condition in the female population caused by the partial or complete loss of X-Chromosome. Previous case reports in the literature and prior studies established the association between Turner’s syndrome and multiple Autoimmune Diseases (AID). We present a 38-Year-old female with Turner’s syndrome, Thyroid disease and multiple admissions for Fistulizing Crohn’s disease. X chromosome deletions and alterations predispose to auto-immune antibodies per prior studies......ReadMore

Peng Cheng, Hai-Yang Liao and Hai-hong Zhang*

DOI : 10.32474/LOJMS.2022.06.000230

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Osteosarcoma (OS) is the most common bone malignancy in children and adolescents. Despite the efficacy of multiscientific and multimodal therapies for OS, the prognosis of OS is not satisfactory, which highlights the need to find more effective therapies. The NF-κB pathway is a highly complex and unique intracellular signaling pathway, whose abnormal expression has been implicated in a variety of human diseases, including cancer, spinal cord injury, degenerative disc changes, traumatic brain injury, and tuberculosis. NF-κB pathway is considered to be a common signaling pathway in human cancer. Multiple studies have shown that this pathway is often abnormally expressed in OS and regulates the pathophysiological processes of osteosarcoma, such as gene expression, cell proliferation and apoptosis, invasion, migration and tumor .....ReadMore

Bhumika Dua, Rajaram Sharma*, Tapendra Tiwari and Saurabh Goyal

DOI : 10.32474/LOJMS.2021.06.000228

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Budd-Chiari syndrome (BCS) is described as hepatic venous outflow obstruction. The obstruction may occur at the level of intrahepatic Inferior Vena Cava (IVC) or any of the hepatic veins. It may be primarily due to hypercoagulable or pro-thrombotic state or secondary to obstruction of hepatic veins, inferior vena cava or right atrium. Long-standing BCS may cause sinusoidal congestion, ischaemic injury to hepatocytes, fibrosis, cirrhosis and may eventually lead to Hepatocellular Carcinoma (HCC) [1-4]. The clinical presentation of the patient varies from mild symptoms to acute fulminant hepatic failure, with the majority of patients presenting in the chronic stage [5,6]. The severity of presentation depends on the degree of venous obstruction and formation of veno-venous collaterals [7]. Both BCS and HCC are usually diagnosed by a combinati.....ReadMore

Jihane EL Mandour*, Amine Cherraqi, Ouadie EL Menaoui, Meryem Edderai and Jamal EL Fenni

DOI : 10.32474/LOJMS.2021.06.000227

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Polysplenia can be isolated or associated with other congenital malformations that are part of the polysplenia syndrome. Polysplenia syndrome is a rare congenital disease characterized by the presence of two or more spleens (Figure 1) and affection of other asymmetric organs It is more commonly identified in childhood than in maturity. It’s an uncommon heterotaxy condition that affects one out of every 250 000 live births. Several studies have attempted to categorize the wide range of abnormalities into asplenia and polysplenia. Polysplenia has an underlying etiology that is unknown. it has been linked to a variety of causes, including embryonic, genetic, and teratogenic components [1,2]. It is characterized by an abnormal arrangement of thoracic and abdominal organs. The variable involvement of these different organs results in a clini.....ReadMore

Mohammad Rahmat Ullah Siddique*, Monirul Islam, Professor Md. Shahidullah Sikder, MA Wahab, Md Alauddin Khan and Nahid Pervez khan

DOI : 10.32474/LOJMS.2021.06.000226

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Hypothyroidism commonly has dermatologic manifestations. The endocrinopathies that may have cutaneous findings, in hypothyroidism the physician most likely see the skin reflect the functional capacity of the thyroid gland. To find out the cutaneous manifestations of a hypothyroid patient in tertiary care hospital of Bangladesh. The descriptive type of cross-sectional study will be conducted in the Department of Dermatology and Venereology, Bangabandhu Sheikh Mujib Medical University, Dhaka, during the period of July 2017 to June 2018. In this study we have taken 100 patients who have skin complaints and symptoms of hypothyroidism and parameters were noted regarding history, cutaneous symptoms and signs. Among the 100 patients, 22% were male and 78% were female with mean age 41 yrs. Most common cutaneous symptom was pruritus (76%), followe.....ReadMore

Gayathri Delanerolle*, Suchith Shetty, Vanessa Raymont, Dharani Hapangama, Nyla Haque, Jian Shi, Salma Ayis, Peter Phiri and Ashish Shetty

DOI : 10.32474/LOJMS.2021.05.000225

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Machine Learning (ML) is a common Artificial Intelligence (AI) method. The use of ML offers the opportunity to develop better data mining techniques in order to analyse complex clinical interactions with a large number of variables. ML models should provide “real-time” clinical support reducing clinical risk to patients with model-agnostic interpretation to deduce a more specific clinical decision. Whilst ML algorithms have been used as the relatively “new kid on the block” in healthcare practice, they have shown promising results in predicting disease outcomes or risks in a variety of diseases such as depressive disorder, Type 2 diabetes mellitus, postoperative complications and cardiovascular diseases. However, patients suffering from a chronic condition are likely to have more than one condition requiring simultaneous attention.....ReadMore

Langberg C, Hadley CL, Midtrevold M, Edvardsen HME, Molden E, Shafiei M and Jacobsen D*

DOI : 10.32474/LOJMS.2021.05.000224

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Background: With increasing use and availability of Quetiapine (Q) the number of self-poisonings has increased. The toxic effects of Q may be lethal and an increased knowledge of these poisonings may improve the outcome in these patients. Methods: Two cases of Q poisoning are presented, one with toxicokinetic data of both Q and NQ, as well as a literature review of Q poisoning. Epidemiological data on Q poisoning in Norway and the frequency of these poisonings in the forensic reports are presented in the supplementary material. Results: The two cases of severe Q poisoning, of whom one was fatal, illustrated the cardiovascular complications and the convulsions also found in the literature review. The toxicokinetic data indicated a biphasic elimination of Q and a persisting high level of the metabolite N-desalkylquetiapine (NQ) even after.....ReadMore

Daniel Perejón López*, Serna Arnaiz MC, Galvan Santiago L, Siscart Agusti J and Laura Gasco Serna

DOI : 10.32474/LOJMS.2021.05.000223

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Attention Deficit Hyperactivity Disorder (ADHD) starts in childhood with symptoms of hyperactivity, impulsivity, and/ or inattention. These symptoms affect cognitive, academic, behavioral, emotional, and social functioning [1]. The reported prevalence of ADHD in children ranges from 2% to 18% depending on the diagnostic criteria used and the population studied (e.g. primary care versus hospital) [1]. The estimated prevalence in school-aged children is 8% to 11%, making it one of the most common disorders of childhood [2]. According to a multicenter meta-analysis of 175 studies involving 1,023,071 individuals, the estimated pooled prevalence of ADHD in adults aged over 36 years was 7.3% (95% CI, 6.7-7.8) [3]. Epidemiological studies of ADHD in the adult population have estimated a current prevalence of 3.4% nationwide and 4.4% in the Unite.....ReadMore

Yasser Mohammed Hassanain Elsayed*

DOI : 10.32474/LOJMS.2021.05.000222

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Rationale: Typhoid (enteric) fever is one of the most serious infections worldwide. Drug-induced diseases is a vital issue in toxicology and clinical medicine. Ciprofloxacin is a fluoroquinolone antibiotic can cause a serious or irreversible disabling side including tendon, bone, muscles, joints, nerves, and central nervous system problems. Patient concerns: A middle-aged married male patient presented to the physician outpatient clinic with a typhoid fever progress to severe neck pain and weakness of both upper extremities. Diagnosis: Ciprofloxacin-induced bilateral upper limb paresis and cervical spinal stenosis. Interventions: Magnetic resonance imaging Electrocardiography, Widal test, and decompressive surgical neck repair. Outcomes: The deterioration after decompressive surgical neck repair had happ.....ReadMore

Romaszko Wojtowicz A*, Buciński A2 and Doboszyńska A

DOI : 10.32474/LOJMS.2021.05.000221

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Considerable progress has been observed over the recent few decades in diagnosis, treatment, and prognosis of oncological patients. The purpose of this study was to detect survival time in patients with single lung cancer and Multiple Primary Neoplasms (MPNs) with last lung cancer. Data regarding multiple neoplasms of which the last one was a lung cancer (124 patients) were collected from January 2013 to December 2017, whereas the information about single lung cancers (601 patients) from January 2015 to December 2016. The analysis showed that the survivability of patients with a single lung cancer (0.17 years; SD: 0.82) is considerably shorter than that of patients with multiple neoplasms (6.20 years; SD: 6.47) (p<0.05), counted both from the diagnosis of the fi.....ReadMore

Igor Klepikov

DOI : 10.32474/LOJMS.2020.05.000220

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The COVID-19 pandemic has disrupted the usual rhythm of our lives, becoming a surprise, a serious problem and a great challenge for all segments of society, but the prospects for overcoming this situation and returning to previous social standards remain unclear. Cautious and uncertain forecasts of specialists even for the near future and daily updates in the media of the number of infected and dead sow a sense of anxiety, and medical confessions about the lack of effective treatment create a sense of insecurity......ReadMore

Zakaria M Sawan

DOI : 10.32474/LOJMS.2020.05.000219

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A field experiment on cotton yield resulted in a non-statistically significant interaction. An approach for follow-up examination between treatments based on least significant difference values was suggested to identify the effect regardless of insignificance. It was found that the classical formula used in calculating the significance of interactions suffers a possible shortage that can be eliminated by applying a suggested revision......ReadMore

Sorush Niknamian

DOI : 10.32474/LOJMS.2020.05.000218

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Introduction: Radioactive iodine is the effective therapy in thyroid cancer. The aim of this study is to evaluate the serum tumor markers in patients under the therapy with radioactive iodine 131. Material and Methods: 45 cases of female patients aged 16-60 years with thyroid cancer surgery referred to the nuclear medicine department of Nemazi hospital for (iodine treatment after surgery) were selected. The selection was on the basis of interviewing and information of patients is consent forms. Only patients with thyroid cancer and referred for the first time without any other diseases were chosen for this study. The selected patients were prescribed a dose of 150 mCi of I-131. From each patient,4 mL of chelated serum for serological studies on tumor markers and 2 mL of oxalated serum for spectrophotometry studies on cell death were used.....ReadMore

Shu-Qing Yang

DOI : 10.32474/LOJMS.2020.05.000217

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For every epidemic, the public and decision-makers worry that the number of infected people will be far more than the healthcare system can afford, thus it is important to predict the cases which need medical services. This is similar to cases of natural disasters such as floods when a devastating outcome occurs with incoming and outgoing water volume being higher than a river’s storage capacity. The similarities between floods and epidemics inspire a modified rainfall-runoff model, I&α. This novel model focuses on the prediction of active cases, i.e., y0, which measures the number of people who need medical services. This model is based on the past data for the prediction of future epidemic trends. This model can effectively predict the maximum y0 and its peak date when applied to model COVID-19, with an average error of 3.8% and 2.7 .....ReadMore

Namir Halilović and Azra Bašić Halilović

DOI : 10.32474/LOJMS.2020.05.000216

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In this paper, we examined the possibility of using high performance thin layer chromatography for the qualitative and quantitative determination of Centralites 1 (1,3-diethyl-1,3-diphenylurea) and 2 (1,3 dimethyl-1,3-diphenylurea). For this purpose,we developed new method in which we find an appropriate mixture of carrier solution, as a key factor in the development of the method, using a mixture of toluene, acetone and cyclohexane. We confirmed in the experiment that mixtures of 9 vol. toluene and 1 vol. acetone for Centralites 1 or 2, and 4 vol. toluene and 6 vol. cyclohexane for diphenylamine stabilizer, are appropriate. Experiments have shown that this method can be used in the testing of propellants, tested on mine caliber of 120 mm. The results of the experiment are proved by high performance liquid chromatography method. The resul.....ReadMore

Boming Liao, Zezhou Wu, He Luan, Jianglong Qin, Fang Xiao and Peiqi Wan

DOI : 10.32474/LOJMS.2020.05.000215

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Background: The aim of this pilot study was to compare the intracranial pressure (ICP) control between the continuous lumbar drainage (CLD) and repeated lumbar puncture (LP) on the patients with HIV-associated Cryptococcal Meningitis (CM). Methods: From January 2017 to January 2019, a total of forty patients with HIV-associated CM patients were randomized and allotted into CLD or repeated LP groups, respectively. During the first two weeks of the treatment, either CLD or LP were used to control the ICP pressure except the routine antifungal therapy was given following the consensus and guidelines of CM. The ICP pressure, protein concentration and cell count from CSF were assayed and compared between the two groups. Result: All the patients were survived. At the day 14 post treatment, a drop in ICP was observed among patients and clinical .....ReadMore

Nida Tabassum Khan and Muhammad Jibran Khan

DOI : 10.32474/LOJMS.2020.05.000214

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With the dynamic new advances and techniques, we were likewise acquainted with more up to date types of carbon, for example, graphene quantum dots, graphene oxide, fullerenes, and carbon-based nanotubes. In the realm of nanotechnology, particularly, carbon nanomaterials have been a forward leap; from tranquilize liberation to synthetics, carbon’s allotropes have demonstrated to be harder than steel and more productive than some other material......ReadMore

SalouaKhalfaoui, Abdellah El Marbouh, Mustapha El Abbassi

DOI : 10.32474/LOJMS.2020.05.000213

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The burn is a frequent accident most often of domestic origin. Causal agents are diverse and can be associated. The quality of the care depends initially on a good diagnosis of the different lesions with precision and description of their characteristics which play a primordial role in the evaluation and the prognosis of the burn......ReadMore

Camilo EstarlingCazorla Hernández,Luis Andrés Dulcey Sarmiento, Jonathan Antonio Pineda Parada, Hector Alonso Moreno Parra, Jose Jorge SampayoZuletaCiro Alfonzo la Cruz

DOI : 10.32474/LOJMS.2020.05.000212

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Objectives: To establish the prognostic role of the Glasgow and FOUR coma scales in patients with severe cranioencephalic trauma of the adults emergency of the autonomous university hospital of the andesmeridavenezuela January - June 2018. Materials and Methods: Prospective, field and longitudinal cut. We selected those patients older than 18 years with a diagnosis of cranial encephalic trauma, the corresponding variables were evaluated in each patient of the sample. Results: 56 patients 86.6% men and 13.4% women, the average age was 26.9 years, the largest age group corresponded to those under 35 years, 44 (79%), the traffic accidents were the the main cause of head brain trauma 49 (87%), cerebral edema was the main tomographic finding, all neurotomographic findings showed statistical significance. Total mortality was 12 (21%) patients.....ReadMore