Lupine Publishers Group

Fatimah Kharal, Sakshi Bai, Muhammad Hassan Hafeez, Muhammad Shikaib, Ahmed Abdullah, Sharmeen Naz, Sarah Khalid, Muhammad Ali Khan* and Fahmeeda Khatoon Junejo

DOI : 10.32474/LOJMS.2022.06.000235

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The Thyroid Carcinomas (TCs) have 5 main histological types: papillary, follicular or differentiated, poorly differentiated, anaplastic (the most destructive type), and medullary TC. Significant variability has been observed, both among and within neoplasms, in these different types of TCs...... ReadMore

Pavan T Lanjewar*, Sarojini Jadhav, Omar Khan and Vishakha Iyer

DOI : 10.32474/LOJMS.2022.06.000234

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Branchial arch anomalies are one of the differential diagnoses in patients of neck pathology during early childhood. Branchial anomalies of second arch being the most common among these anomalies. A complete fistula communicating with a branchial arch cyst is a very rare congenital anomaly of the branchial apparatus...... ReadMore

Uri Galili*

DOI : 10.32474/LOJMS.2022.06.000233

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The Covid-19 Omicron subvariants BA.1, BA.2 and BA.3 which appeared at the end of 2021 in South Africa contain ~50 mutations in comparison to the original Wuhan strain, many of which unique to each subvariant. This number of mutations is much higher than that observed in other Covid-19 variants or in variants of other viruses. Such high number of mutations in genetic material is usually induced in nature by ionizing-radiation...... ReadMore

Saad Kadhom Hamid Al Zawi*

DOI : 10.32474/LOJMS.2022.06.000232

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Understanding the effects of anesthesia and the techniques used in eye surgery are very important to providing perioperative anesthesia care. This study aimed to identify the type of anesthesia was used of ophthalmic surgery and comparison between them during the study period. A cross-sectional study was conducted in all the hospital which included the eyes clinic in Baghdad. All the cases admitted from the 1st of January 2020 up to the end of December 2020 were enrolled in this study. We included all the cases of various reasons. Semi-structured questionnaire was used to collect the information on them. The sample size was 27,010 cases. Data was described by using the descriptive statistics such as frequency, percentage, Fisher chi-square, and p. value. STATA version 14 statistical package was used to analyze the data. There ..... ReadMore

Revanth Katamareddy, Saraswathi Lakkasani*, Gowthami Sai Kogilathota Jagirdhar, Scott Digiacomo and Yatinder Bains

DOI : 10.32474/LOJMS.2022.06.000231

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Turner’s syndrome is a genetic condition in the female population caused by the partial or complete loss of X-Chromosome. Previous case reports in the literature and prior studies established the association between Turner’s syndrome and multiple Autoimmune Diseases (AID). We present a 38-Year-old female with Turner’s syndrome, Thyroid disease and multiple admissions for Fistulizing Crohn’s disease. X chromosome deletions and alterations predispose to auto-immune antibodies per prior studies...... ReadMore

Peng Cheng, Hai-Yang Liao and Hai-hong Zhang*

DOI : 10.32474/LOJMS.2022.06.000230

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Osteosarcoma (OS) is the most common bone malignancy in children and adolescents. Despite the efficacy of multiscientific and multimodal therapies for OS, the prognosis of OS is not satisfactory, which highlights the need to find more effective therapies. The NF-κB pathway is a highly complex and unique intracellular signaling pathway, whose abnormal expression has been implicated in a variety of human diseases, including cancer, spinal cord injury, degenerative disc changes, traumatic brain injury, and tuberculosis. NF-κB pathway is considered to be a common signaling pathway in human cancer. Multiple studies have shown that this pathway is often abnormally expressed in OS and regulates the pathophysiological processes of osteosarcoma, such as gene expression, cell proliferation and apoptosis, invasion, migration and tumor ..... ReadMore

Bhumika Dua, Rajaram Sharma*, Tapendra Tiwari and Saurabh Goyal

DOI : 10.32474/LOJMS.2021.06.000228

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Budd-Chiari syndrome (BCS) is described as hepatic venous outflow obstruction. The obstruction may occur at the level of intrahepatic Inferior Vena Cava (IVC) or any of the hepatic veins. It may be primarily due to hypercoagulable or pro-thrombotic state or secondary to obstruction of hepatic veins, inferior vena cava or right atrium. Long-standing BCS may cause sinusoidal congestion, ischaemic injury to hepatocytes, fibrosis, cirrhosis and may eventually lead to Hepatocellular Carcinoma (HCC) [1-4]. The clinical presentation of the patient varies from mild symptoms to acute fulminant hepatic failure, with the majority of patients presenting in the chronic stage [5,6]. The severity of presentation depends on the degree of venous obstruction and formation of veno-venous collaterals [7]. Both BCS and HCC are usually diagnosed by a combinati..... ReadMore

Jihane EL Mandour*, Amine Cherraqi, Ouadie EL Menaoui, Meryem Edderai and Jamal EL Fenni

DOI : 10.32474/LOJMS.2021.06.000227

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Polysplenia can be isolated or associated with other congenital malformations that are part of the polysplenia syndrome. Polysplenia syndrome is a rare congenital disease characterized by the presence of two or more spleens (Figure 1) and affection of other asymmetric organs It is more commonly identified in childhood than in maturity. It’s an uncommon heterotaxy condition that affects one out of every 250 000 live births. Several studies have attempted to categorize the wide range of abnormalities into asplenia and polysplenia. Polysplenia has an underlying etiology that is unknown. it has been linked to a variety of causes, including embryonic, genetic, and teratogenic components [1,2]. It is characterized by an abnormal arrangement of thoracic and abdominal organs. The variable involvement of these different organs results in a clini..... ReadMore