Andrew Xing, Zhixin Tang and Zhiguang Huo*

DOI : 10.32474/LOJMS.2024.06.000249

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Lung cancer is the most common cancer in men and the 2nd most common cancer in women worldwide with more than 2.2 million new cases in 2020 [1]. Besides its high prevalence, the fiveyear overall survival rate for patients with lung cancer is very low in comparison to the other major type of malignancies, barely reaching to 23% in the United States of America in 2023 [2] while such rates are even lower in many other countries and regions [3]. The rather poor clinical outcome of patients with lung cancer are largely due to the late diagnosis of lung cancers, the majority of which are at clinical stage upon diagnosis, the limited efficacies and significant toxicities of current therapeutic treatments, the rapid acquisition of drug resistance, and the associated high rate of disease recurrence and progression...... ReadMore

Urmanova Yu M*, Khudaybergenov Sh A, Alieva DA, Khaydarova RT, Min Ji Kim and Khodgaeva FS

DOI : 10.32474/LOJMS.2024.06.000248

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The structure of arterial hypertension generally consists of cases of essential hypertension and symptomatic, the latter, according to WHO data, today is about 30% [1-3]. Endocrine hypertension of adrenal origin ranks second in frequency among symptomatic hypertension after renal hypertension and accounts for 6-10% [4-5]. Currently, the diagnosis and treatment of arterial hypertension of adrenal origin continues to be an urgent problem for both therapists and endocrinologist surgeons. This category of patients, along with hormonal disorders, has arterial hypertension, which is not amenable to drug correction, often with a severe clinical course and the development of complications. In the structure of all causes of increased blood pressure, secondary arterial hypertension accounts for up to 20%, of which 15-25% is due to arterial hyperten..... ReadMore

Bruno Silva Peixoto de Carvalho, Rômulo Augusto Lucena de Vasconcelos* and Adriano Almeida Calado

DOI : 10.32474/LOJMS.2024.06.000247

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Phimosis, by far the most common medical indication for circumcision, can be defined as a narrowing of the preputial orifice, leading to an inability to retract the foreskin, or prepuce, over the glans penis [1]. The proportion of boys circumcised during childhood varies markedly by country, by religion and, o some extent, by socioeconomic group. Various Paediatric societies have developed position statements on circumcision. These statements generally conclude that there is insufficient evidence to recommend routine neonatal circumcision [2]. In the last 30 years, due to controversies regarding the medical indications for circumcision, together with the emergence of several entities opposed to circumcision, this surgery started to be questioned. This has led to widespread interest in developing an effective clinical therapy. Initial s..... ReadMore

Urmanova Yu M*, Mirtukhtaeva MB, Khudaybergenov Sh A, Khaydarova RT, Alieva DA and Yunusova Kh R

DOI : 10.32474/LOJMS.2024.06.000246

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Pituitary adenomas are mostly benign, and their first symptoms are associated with hypersecretion of hormones or hypopituitarism, when normal pituitary tissue is compressed [1,2]. Some of these tumors may be associated with evidence of infiltration, destruction, and invasion of adjacent tissues during their development, known as invasive pituitary adenomas. This term was first proposed by Jefferson [3,4], who considered these adenomas to be local malignant tumors. However, there is still no clear definition of aggressiveness. Some authors suggest that they are often recurrent tumors that have a large volume, accelerated growth, invasion of adjacent structures and resistance to multimodal treatment...... ReadMore

Benjamin Scherlag*

DOI : 10.32474/LOJMS.2024.06.000245

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Newsweek. Published March 1, 2021, Near-Death Experiences Can Transform a Person in Seconds Says Scientist by Aristos Georgiou Science and Health Reporter People who come close to death often report remarkable experiences, that have long been dismissed by the medical profession. Dr. Bruce Greyson, a specialist in psychiatry and neurobehavioral sciences at the University of Virginia-and one of the world’s leading experts on near-death experiences-has been studying these strange phenomena for more than four decades. Newsweek spoke to Dr Greyson about his work and what people’s reports of near-death experiences (NDEs) reveal about the nature of life, death and consciousness. This interview has been edited for length and clarity...... ReadMore

Gayathri Delanerolle, Jintong Hu, Heitor Cavalini, Katharine Barnard-Kelly, Kathryn Elliot, Vanessa Raymont, Shanaya Rathod, Jian Qing Shi and Peter Phiri*

DOI : 10.32474/LOJMS.2023.06.000244

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The Qualtrics Core XM platform was used to deploy the questionnaire where a quantitative analysis was conducted. The qualitative part of the study used the Microsoft Teams digital application to complete the interviews. Various validated mental health assessments were administered: Vancouver Index of Acculturation (VIA), Hospital Anxiety and Depression Scale (HADS), Insomnia Severity Index (ISI), Pandemic Stress Index (PSI), Burnout Assessment Tool-12 (BAT-12), General Self Efficacy Scale (GSE) and The Everyday Discrimination Scale (EDS)...... ReadMore

Peter Phiri, Jian Qing Shi, Heitor Cavalini*, Katharine Barnard-Kelly, Sana Sajid, Vanessa Raymont, Shanaya Rathod, Gayathri Delanerolle

DOI : 10.32474/LOJMS.2023.06.000243

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An evidence-based framework was developed using qualitative and quantitative data, as reported by the EPIC observational study. A framework methodology was used to analyse qualitative and quantitative data to identify themes. The themes were used to identify sub-themes that were codes with illustrative quotes...... ReadMore

Chaoqin Mao, Yueshan Xiong and Cheng Fan*

DOI : 10.32474/LOJMS.2023.06.000241

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Deep Vein Thrombosis (DVT) is a serious condition that can lead to significant morbidity and mortality in hospitalized patients. Early identification and prevention of DVT-related coagulation abnormalities are crucial for patient outcomes. While Conventional Coagulation Assays (CCAs..... ReadMore