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Earlier we had reviewed the roles of Kisspeptins in reproduction in 2012 and subsequently the confusion over progesterone in positive feedback effects with challenges in the earlier explanations offered. Since then, a lot of work has been done in rodents as the mammalian species to explain the part of epigenetics further . Estrogen generated by the ovarian follicles possess a crucial part in the central mode regulating reproduction through control of gonadotropin releasing hormone( GnRH) liberation via its negative along with positive feedback effects in case of female mammals. It has been well acknowledged that estrogen receptor-α(ER-α) modulates both negative along with positive feedback effects, however precise targets have continued to be enigmatic for over20 yrs. Subsequent to the invention of Kisspeptin(Kp) neurons in the fo..... ReadMore -
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Menopause is a natural biological process leading to a transition from a reproductive to a non-re- productive state experienced universally by all women due to ovarian failure. The age at which menopause occurs is generally between 45 and 55 years, with an average onset of 51 years...... ReadMore -
Short CommunicationView abstract
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a) I Kant, Lorenz’s predecessor, is said to have said “obeyed categoric imperatives”. b) The female movements of the pelvis (of the dorsolumbar hinge), offered as an evocative spectacle, are always popular with the male public. Some women who are harassed or paid perform them deliberately, with authority, to trigger the ejaculation of an annoying or paying partner as quickly as possible...... ReadMore -
Mini ReviewView abstract
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Infertility is on increase with rising trend observed in carrier-oriented couples. The influence of infertility can be immense and devastating. The impact affects the social wellbeing with loss of self-esteem, disappointment and depression. The investigations of many such couples do not exhibit any perceptible cause and are labeled as ‘unexplained infertile’ - which accounts for around 15-30 percent of the cause of infertility. Such couples have normal ovulatory function, normal semen analysis, normal tubal patency and normal endometrial cavity. It is often hard to explain to such couples their inability to reproduce. The vital step in conception is the efficacious implantation which necessitates a normal and functioning embryo at developmental stage of blastocyst, a receptive endometrium and a synchrony between embryonic and maternal..... ReadMore -
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Background: Chorioamniotic separation (CAS) at the time of amniocentesis is a risk factor for an elevated postprocedural complication rate after standard amniocentesis and should be excluded before amniocentesis. Objectives: The aim of this study was to quantify procedure-related risks after amniocentesis (AC) with a 29G-needle in cases of chorioamniotic separation (CAS) and evaluation of perinatal outcome in CAS after 15 weeks’ gestation (GW). Materials and Methods: Retrospective analysis of genetic amniocentesis with an atraumatic 29G-needle after 15 completed GW in pregnancies, in which the fetal membranes were not fused yet. Included into the study were women with at least 15 completed weeks of gestations referred for second trimester amniocentesis to identify fetal chromosomal aberrations aged 16 to 44 years. Results: 437 Amn..... ReadMore -
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It is Konrad Lorenz, who described the period of sensitivity necessary for the epigenetic maturation of certain biological functions. The orgasmic reflex, the foundation of the erotic function, is one of these phenomena which can only emerge during a sensitive period of childhood. It is the individual, guided by the situation his hands, and by grooming, who discovers the power of the orgasmic zones. Thus, a first infantile phase of development, autoerotic, is imposed on the use of the external genitalia. Before the access to the second, adult, heteroerotic phase. Ignoring, blaming or antagonizing this autoerotic phase is not only a general fault of civilization, mentioned here, with sometimes dramatic consequences. but also, a scientific error...... ReadMore -
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Objectives: The objective was to describe and compare self-reported changes in the menstrual cycle in females who had COVID-19. Methods: This was a cross sectional study conducted through an online questionnaire between January 1, 2021, and September 30, 2021. Included were females aged between 13 and 52 years who previously acquired COVID-19. Participants were divided into two groups; one group were females who experienced change in their menstrual cycle following COVID-19 infection and the other group were those who did not have any change. Results: A total of 341 participants were included, 183 (53.7%) experienced change in their menstrual cycle. The mean age was 31.01±8.97 years in those without change and 32.21±9.09 years in those who had changes. Ninety (57.0%) in the unchanged cycle group had co..... ReadMore -
Case ReportView abstract
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Endometriosis has a broad spectrum of presentation The purpose of this article is to familiarize the gynecologist with the wide spectrum of pelvic and extra pelvic endometriosis and to review the distinctive imaging findings. Its clinical diagnosis could be challenging since it is often confused with infection, abscess, hematoma, and tumors. We hereby report a series of multiple endometriosis presentations appearing during pregnancy, at episiotomy and perineum, as well as after cesarean delivery and hysterectomy. The primary modality of treatment is surgical removal of the lesions, though hormonal therapy is also applied...... ReadMore