Lupine Publishers Group

Chukwubuike Kevin Emeka*, Igweagu Chukwuma Paulinus and Anijunsi Livinus Patrick

DOI : 10.32474/CTGH.2022.03.000173

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Intussusception is considered an acquired disease of infants and most of the times, the etiology is not known (idiopathic). The presence of a pathologic lead point causing intussusception is uncommon in infants. The aim of this study was to evaluate our experience with regards to infants who were managed for intussusception and were found to have pathologic lead point (PLP) at surgery...... ReadMore

Jingying Xing, Chaochao Chen, Yiyao Chen, Cheng Lan*

DOI : 10.32474/CTGH.2022.03.000172

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Intestinal fibrosis is the intestinal tissue’s response to the injury caused by recurrent chronic inflammation. It is a common and serious complication of inflammatory bowel disease, characterized by excessive proliferation and accumulation of extracellular matrix in the intestine. The mechanism of its formation may be related to the excessive proliferation of intestinal stromal cells, extracellular stroma, epithelial-mesenchymal transformation and the interaction of various cytokines..... ReadMore

Amir Mohammadamini*

DOI : 10.32474/CTGH.2022.03.000171

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It turns out that it has attracted the attention of many psychologists, psychiatrists and researchers. It is said that this disorder has always existed throughout human history and today it has a significant proportion of neurotransmitters. The severity and persistence of this disorder sometimes reaches such a level that it completely reduces the strength and efficiency of the person and leaves a crippling effect on the patient’s personal and social life...... ReadMore

Larbaoui K and Ghouini A*

DOI : 10.32474/CTGH.2022.03.000170

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The distribution of body fat is actually more important than the total amount of fat mass when it comes to cardio-metabolic risk. Abdominal visceral fat is just one low share of fat mass, since the majority of fat is subcutaneous (80% in men, 90% in women), but seems to play a more important role than the rest of the adipose tissue. Indeed, the fatty tissue has 2 compartments with characteristics different metabolisms. In our work, we investigated the influence of age and sex on the propensity for the development of visceral fat in a target population such as obese diabetics. At the end of our study, it clearly appears that age is a risk factor for increased visceral adipose tissue and that men are more exposed than women, although the BMI is higher in the latter...... ReadMore

Javier Orcajo Rincón* and Alonso Farto Juan Carlos

DOI : 10.32474/CTGH.2022.03.000169

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Among the intra-arterial techniques used in primary and metastatic liver pathology, radioembolization with yttrium-90 microspheres has been the one that has evolved most dramatically in recent years and the one that has positioned itself in the earliest stages of management of hepatocellular carcinoma (HCC) in current clinical guidelines [1,2]...... ReadMore

Merit Kase, Clas-Göran AF Björkesten, Veli-Jukka Anttila, Jonna Jalanka, Juuso Arkkila, Perttu Arkkila and Pauliina Molander*

DOI : 10.32474/CTGH.2022.03.000166

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Objectives: The novel coronavirus SARS-CoV2 became a worldwide pandemic in 2020. It is known that patients with inflammatory bowel disease (IBD) are at an increased risk of infection, particularly when on immunosuppressive therapy. The outcomes of COVID-19 in IBD patients remain somewhat unclear. Methods: This Finnish retrospective observational cohort study enrolled 74 patients with an established IBD diagnosis and a confirmed COVID-19 infection. Patient data (age, sex, body mass index, IBD type, biochemical and clinical activity, comorbidities [Charlson comorbidity index [CCI]) and symptoms of COVID-19 were compared with hospitalization due to the COVID-19 infection. Results: We found that older age (p < 0.01) and comorbidities (CCI score higher than one [p < 0.01]) were associated with hospitalization due to COVID-19 ..... ReadMore

N Gokarneshan*, PG Anandha Krishnan, D Haritha, Navya Sudheer and Fousul Inaya

DOI : 10.32474/CTGH.2022.03.000165

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Curcumin is a naturally occurring hydrophobic polyphenol compound. It exhibits a wide range of biological activities such as antibacterial, anti-inflammatory, anti-carcinogenic, antifungal, anti-HIV, and antimicrobial activity. In this research work, antimicrobial curcumin nanofibrous membranes are produce by an electrospinning technique using the Eudragit RS 100 (C19H34ClNO6) polymer solution enriched with curcumin. The morphology and chemistry of the membrane are analyzed using scanning electron microscopy (SEM) and Fourier transform infrared (FTIR) spectroscopy. Kirby Bauer disk diffusion tests are carried out to examine the antibacterial effectiveness of the membrane. Experimental results show that the nano fibers produced are of uniform thickness morphology and curcumin is successfully incorporated into the nanofibrous ..... ReadMore

Raquel Susana Torrinhas, Paulo César Ribeiro, Yassmin Syagha, Anna Carolina Pompermayer Coradelli and Dan Linetzky Waitzberg*

DOI : 10.32474/CTGH.2022.03.000164

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Extra pulmonary symptoms may contribute to poor outcome in COVID-19. We compared the frequency of gastrointestinal and sensory manifestations (GSM) between mild and severely ill patients with COVID-19, alone or combined with Classic Respiratory Manifestations (CRM). Hospitalized patients with COVID-19 (n = 357) were classified according to their disease severity by using a neutrophile/lymphocyte ratio value ≥18 for severe illness. Presence of CRM and baseline clinical data were recorded. Presence of >3 liquid evacuations per day (diarrhea), decreased usual bowel movements (constipation), nausea/vomiting, lack of appetite (anorexia), abdominal pain, loss of taste (dysgeusia) and/or loss of smell (anosmia) were personally recorded by the investigators at the study admission. Severely ill patients (47.3%) presented worse clinical markers..... ReadMore