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Review Article
Nasser Mikhail* and Soma Wali View abstract
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Tirzepatide was recently approved in the US for treatment of type 2 diabetes. This agent is currently under investigation for use as anti-obesity agent in individuals without diabetes. In a large phase 3 clinical trial, mean percentage reductions in body weight were 15.0%, 19.5%, 20.9%, and 3.1% with weekly subcutaneous injections of tirzepatide 5 mg, 10 mg, 15 mg, and placebo at 72 weeks, respectively (P<0.001 for all comparisons with placebo)...... ReadMore -
Research Article
L Aponte Becerra, B Galindo Mendez, F Khan, V Lioutas, P Novak, CS Mantzoros , LH Ngo and V Novak* View abstract
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This randomized, double-blinded trial consisted of 24-week INI or placebo treatment once daily and 24-week follow-up. Safety outcomes were: 1) Short-term effects on glycemic variability, hypoglycemic episodes on continuous glucose monitoring (CGM) at baseline and on-treatment. 2) Long-term effects on glucose metabolism and weight on INI/placebo treatment and post-treatment follow-up. Of 86 screened subjects, 14 were randomized, 9 (5 INI, 4 Placebo) completed CGM at baseline and on-treatment, and 5 (2 INI, 3 Placebo) completed treatment and follow-up...... ReadMore
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Opinion
Aristeidis Giannakopoulos* View abstract
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In recent years, continuous glucose monitoring (CGM) systems have demonstrated their clinical benefits regardless of the insulin delivery method being used. CGM has the ability to depict daily profiles of glucose levels, facilitating timely and fine adjustments towards euglycemia [1]. The basic metric index of CGM, time in range (TIR) (70-180 mg/dl) has been well correlated with HbA1c levels and has the superiority of presenting the magnitude and variations of glycemic excursions [2]...... ReadMore
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Short Communication
Francisco Jiménez Trejo*, Hugo Díaz Aguilar and Isaac González Santoyo View abstract
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After almost more than two years of declaring the presence of the disease named severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) in Wuhan, China -which caused the current COVID-19 pandemic that we are suffering globally as an international health emergency declared by the WHO- in what is now known as the Anthropocene i.e. the time where human activities are generating not only biological but also geophysical changes on a global scale. Currently, the predominant variant -of South African origin- that is advancing globally is known as OMICRON, which has a wider and faster spread, is more contagious, and generates medical conditions mainly in the upper respiratory tract. The World Health Organization (WHO) has been acting under its role with the high leadership of its representatives at the international level; an immedia..... ReadMore
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Research Article
Abdul Malik Bawah* and Reginald A Annan View abstract
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Cardiometabolic Disease (CMD) is a cluster of conditions that increase the risk for cardiovascular events, but its relationship with vitamin D status has not been studied in Ghana. In this cross-sectional study, we investigated the interrelationship between vitamin D status and obesity, type 2 diabetes mellitus, hypertension, and dyslipidemia, and known CMD risk factors, in 302 healthy adults from the Northern Region of Ghana. We also determined their serum vitamin D levels. We compared vitamin D levels and status by the CMD risk factors using Independent t- and Mann Whiney U tests. We evaluated CMD risk factors that predicted vitamin D status using multiple linear and multivariate logistic regressions. Similar between gender, participants’ mean age was 38.78years (SD 10.42years). The females had higher BMI (24.31 SD 7.96 versus 22.52 S..... ReadMore
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Opinion
Francisco Jiménez Trejo*, Félix Rodríguez Fierros, Luis A Herrera and Cristian Arriaga Canon View abstract
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Obesity is a chronic disease that usually begins in childhood-adolescence due in part to being overweight, but something important is that it often continues until adult life and is usually related to other pathologies. Its origin can be multifactorial and at least in Mexico, we can consider it not only as a genetic inheritance but as an example of what we observe in our adult relatives who often repeat or frequently promote a special and inappropriate way of eating, considering that a good part of this problem acquires a more cultural component in our population. In other words, obesity is emerging as “we eat more than we can occupy burning calories daily”...... ReadMore
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Mini Review
Virgínia Regufe* , Raquel Soares, Cristina Barroso and Pedro Von Hafe View abstract
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Obesity is a nutritional disorder which has been increasing exponentially. It is defined as a pathology brought about by an excess of accumulated body fat and may affect the person’s health. Due to its high growth in the last few years, it has become a public health problem, also known as a chronic disease, which has gained relevance in the past few years. Obese people have a significant higher risk of developing diabetes. According to the Annual Report of the National Diabetes Observatory – 2019 Edition, approximately 90% of the population with diabetes was overweight or obese in 2018, thereby indicating a relation between the Body Mass Index (BMI) and diabetes. The report also mentions that the prevalence of diabetes among obese people whose BMI› = 30 is about..... ReadMore
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Research Article
Hoda M Abdellatif* View abstract
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Introduction: As the relationship between periodontitis and type 2 diabetes (T2D) is bidirectional, oral hygiene and compliance with regular dental visits are especially important for wellness in T2D patients. The United States (US) has been identified as a high-income country with significant barriers to accessing healthcare due to cost issues and the necessity of enrolling in a health insurance plan, but level of dental visit compliance and oral health outcomes among diagnosed T2D patients in the US are unknown. The purpose of this analysis was to estimate the number of diagnosed diabetes patients in the US facing unmet need for oral health services and suffering from poor oral health outcomes. Materials and Methods: Data from the Behavioral Risk Factor Surveillance System (BRFSS), a nationally representative health survey in the US, ..... ReadMore
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Archives of Diabetes & Obesity
Archives of Diabetes & Obesity (ADO) are an open access scientific journal, which covers high quality of manuscripts which are both relevant and applicable to the broad field of applied life sciences. Journal aims to reflect contemporary thinking so that professionals can keep pace with the developments in the field of Diabetes & Obesity. Archives of Diabetes & Obesity are an international, peer reviewed Open Access journal which distributes potential papers on metabolism and diverse sorts of Diabetes & Obesity and its clinical research. The extent of the journal envelops the complete study, which incorporates indications cause pathophysiology, treatment and anticipation of diabetes and the investigation of new strategies in the field of diabetic examination like organ transplantation, tissue recovery and remedial developments of diabetes and obesity. The extension additionally incorporates the clinical investigation of all the metabolic pathways that happen in all the living beings. Archives of Diabetes & Obesity (ADO) provide an opportunity to share the information among the medical scientists, researchers, students. The Journal of Nutrition is one of the best Open Access journals of scholarly publishing. The main aim is to publish most complete and reliable source of information on the discoveries and current developments. This Journal invites Manuscripts in all areas of the field and making them freely available through online without any restrictions or any other subscriptions to researchers worldwide. Journal invites all types of Transcripts that which makes journal so informative and effective like Editorials, Research articles, Review articles, Opinion Articles, Mini Reviews, Short Communications, Case reports, etc. as entries.
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