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OpinionView abstract
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In recent years, continuous glucose monitoring (CGM) systems have demonstrated their clinical benefits regardless of the insulin delivery method being used. CGM has the ability to depict daily profiles of glucose levels, facilitating timely and fine adjustments towards euglycemia [1]. The basic metric index of CGM, time in range (TIR) (70-180 mg/dl) has been well correlated with HbA1c levels and has the superiority of presenting the magnitude and variations of glycemic excursions [2]...... ReadMore -
Short CommunicationView abstract
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After almost more than two years of declaring the presence of the disease named severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) in Wuhan, China -which caused the current COVID-19 pandemic that we are suffering globally as an international health emergency declared by the WHO- in what is now known as the Anthropocene i.e. the time where human activities are generating not only biological but also geophysical changes on a global scale. Currently, the predominant variant -of South African origin- that is advancing globally is known as OMICRON, which has a wider and faster spread, is more contagious, and generates medical conditions mainly in the upper respiratory tract. The World Health Organization (WHO) has been acting under its role with the high leadership of its representatives at the international level; an immedia..... ReadMore -
Research ArticleView abstract
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Cardiometabolic Disease (CMD) is a cluster of conditions that increase the risk for cardiovascular events, but its relationship with vitamin D status has not been studied in Ghana. In this cross-sectional study, we investigated the interrelationship between vitamin D status and obesity, type 2 diabetes mellitus, hypertension, and dyslipidemia, and known CMD risk factors, in 302 healthy adults from the Northern Region of Ghana. We also determined their serum vitamin D levels. We compared vitamin D levels and status by the CMD risk factors using Independent t- and Mann Whiney U tests. We evaluated CMD risk factors that predicted vitamin D status using multiple linear and multivariate logistic regressions. Similar between gender, participants’ mean age was 38.78years (SD 10.42years). The females had higher BMI (24.31 SD 7.96 versus 22.52 S..... ReadMore -
OpinionView abstract
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Obesity is a chronic disease that usually begins in childhood-adolescence due in part to being overweight, but something important is that it often continues until adult life and is usually related to other pathologies. Its origin can be multifactorial and at least in Mexico, we can consider it not only as a genetic inheritance but as an example of what we observe in our adult relatives who often repeat or frequently promote a special and inappropriate way of eating, considering that a good part of this problem acquires a more cultural component in our population. In other words, obesity is emerging as “we eat more than we can occupy burning calories daily”...... ReadMore -
Mini ReviewView abstract
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Obesity is a nutritional disorder which has been increasing exponentially. It is defined as a pathology brought about by an excess of accumulated body fat and may affect the person’s health. Due to its high growth in the last few years, it has become a public health problem, also known as a chronic disease, which has gained relevance in the past few years. Obese people have a significant higher risk of developing diabetes. According to the Annual Report of the National Diabetes Observatory – 2019 Edition, approximately 90% of the population with diabetes was overweight or obese in 2018, thereby indicating a relation between the Body Mass Index (BMI) and diabetes. The report also mentions that the prevalence of diabetes among obese people whose BMI› = 30 is about..... ReadMore -
Research ArticleView abstract
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Introduction: As the relationship between periodontitis and type 2 diabetes (T2D) is bidirectional, oral hygiene and compliance with regular dental visits are especially important for wellness in T2D patients. The United States (US) has been identified as a high-income country with significant barriers to accessing healthcare due to cost issues and the necessity of enrolling in a health insurance plan, but level of dental visit compliance and oral health outcomes among diagnosed T2D patients in the US are unknown. The purpose of this analysis was to estimate the number of diagnosed diabetes patients in the US facing unmet need for oral health services and suffering from poor oral health outcomes. Materials and Methods: Data from the Behavioral Risk Factor Surveillance System (BRFSS), a nationally representative health survey in the US, ..... ReadMore -
Research ArticleView abstract
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Background: Impairing in leukocytes function is the main reason of greater susceptibility to infections observed in patients with diabetes mellitus. The distinctive feature of diabetes is dysregulation in glucose distribution in different tissues and cells in organism. There are evidence that downregulation of glucose transport and lack of energy in leukocytes may contribute to the detriment of their functions. We investigated possible positive effects of photobiomodulation therapy on energy supply and functional activity of leukocytes from rats with experimental diabetes mellitus. Methods: The experiments were conducted using male Wistar rats. Fractioning of blood leukocytes was performed in gradient of ficollsodium amidotrizoate density. Energy supply of leukocytes was evaluated using 2-NBDG (2-deoxy-2-((7-nitro-2,1,3-benzoxadiazol4-yl..... ReadMore -
Review ArticleView abstract
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Abstract: We aimed to evaluate effectiveness and safety of weekly subcutaneous (sc) semaglutide for weight reduction, along with diet and lifestyle modifications in severely obese adolescent patients attending an Obesity Unit. In a prospective observational study, 21 severely obese adolescent patients (18 females, mean age 14.95 years, mean baseline body mass index 33.01 kg/m2) were followed for 8.0 months (median) after initiation of sc semaglutide in two different private institutions. Starting dose and dose titration were decided according to best clinical judgement and based upon effectiveness and gastrointestinal tolerance. At final office visit patients averaged a weight loss of 8.32 ±7.65 kg (8.68 ±7.76% baseline body weight). Starting dose was 0.23 mg and final dose was 0.68 mg. Two patients prematurely discontinued treatment an..... ReadMore