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Research ArticleView abstract
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Infective endocarditis is a life-threatening microbial infection of native and prosthetic heart valves, endocardial surface, and/ or indwelling cardiac device. Despite technological advances, the prevalence of infective endocarditis is increasing; and its mortality has not significantly improved. Burkholderia cepacia is a rare cause of infective endocarditis. Burkholderia cepacia prosthetic valve endocarditis (PVE) is extremely rare, with few cases in the literature [1]. Case presentation A-28-years-old man had prolonged fever for two months. He suffered central chest pain at the peak of fever; he also had dyspnea on exertion and palpitation. He had surgical aortic valve replacement (SAVR) mechanical) for severe aortic regurgitation (rheumatic etiology); mitral valve repair (ring annuloplasty) for rheumatic mitral regurgitation; and,..... ReadMore -
Review ArticleView abstract
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The phenomenon of “silent treatment,” recognized as a subtype of psychological aggression within the broader framework of emotional abuse, is a deliberate act of avoiding or ignoring another individual, often in the context of an intimate or familial relationship [1]. This behaviour involves a breakdown in communication, where one party seeks to impose a form of social isolation or ostracism on the other as an act of punishment, manipulation, or control. Despite appearing as an innocuous or even commonplace occurrence in interpersonal disputes, the silent treatment is capable of inflicting substantial psychological distress and harm [2]. While research on the silent treatment is still emerging, preliminary evidence suggests that it is a pervasive phenomenon across cultures and demographic groups...... ReadMore -
Case ReportView abstract
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Anti-thymocyte globulin (ATG) (Equine) and Basiliximab are widely used as anti-rejection therapy in renal transplant recipients with high immunological risks. They are effective and generally well tolerated; however, fatal reactions are rarely reported. We report hypotension 10 hours after injection ATG with resultant right hemiparesis and motor aphasia due to cerebrovascular accident (cerebral infarct)...... ReadMore -
OpinionView abstract
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The author passed out, became disoriented, weakened and could not communicate with others this year (2023). Around 1974, a diet was constructed for him for hypoglycemia. Over and above reducing sugar and fats, the author consumed a diet soda [1-3]. The drink left an “after taste” that was bitter. By adding skim milk, the drink was enjoyable...... ReadMore -
Case ReportView abstract
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38-year-old female with adult polycystic kidney disease had end stage renal disease. She underwent pre-emptive renal transplant from living non-related donor. At the same time, she had right nephrectomy. This case presented advantages of pre-emptive renal transplant as well as doing native unilateral nephrectomy simultaneously at the time of transplant...... ReadMore -
Case ReportView abstract
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Liver abscess is an intra-abdominal infection, generally bacterial, which presents a decrease in mortality rates in the last years due to the systematic use of broad-spectrum antibiotics and advances in diagnostic medicine. However, there are rare cases, such as in biliary abscesses caused by foreign bodies, in which the suspicion comes after refractivity to conservative treatment, and the definitive diagnosis is obtained only during surgery...... ReadMore -
Mini ReviewView abstract
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Having practiced during a long time as a Pedo- Psychiatrist with the Function of Therapeutic Manager in a Hospital department welcoming young with affective or behavioral disorders, we have acquired an experience in various modalities of psychotherapeutic care..... ReadMore -
Mini ReviewView abstract
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Hypoxia is a typical pathological process that develops as a result of a lack of biological oxidation, leading to a disruption in the energy supply of functions and plastic processes in the brain. Hypoxia of the brain is one of the main mechanisms of its damage in traumatic brain injury and acute cerebrovascular accident. With hypoxia, proteases are activated, including Ca2+-dependent (calpains). They are localized outside of lysosomes in membrane structures in the form of an inactive complex with inhibitory proteins (calpastatins). The main functions of calpains are: repair of the cytoskeleton and cell membranes, destruction of receptor proteins and their renewal, activation of enzymes. In this way, hypoxia causes structural and metabolic changes in the neurons of the central nervous system, triggers adaptation mechanisms implement..... ReadMore