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Research Article
Raquel d’ Espiney, Jacek Jablonski, Michal Brys and Juan F Martin Lazaro* View abstract
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ShareBackground: Humidified high flow nasal cannula (HFNC) has been shown to be an effective respiratory support therapy in both primary and post-extubation patients with Type 1 respiratory failure (T1RF). Clinical outcomes using HFNC in patients with hypercapnic respiratory failure or Type 2 respiratory failure (T2RF) are less well understood as research to date has frequently excluded hypercapnic patients. However, there is growing evidence that suggests HFNC could be beneficial in patients with T2RF.Aims: To describe the outcome of patients with T2RF who received primary HFNC and to elaborate a safe algorithm for its use.Methods: We conducted a retrospective observational study on the use of HFNC as a primary treatment in 102 (n=102) consecutive subjects admitted to the Intensive Care Unit (ICU) from August 2015 to June 2017. Vital signs an..... ReadMore -
Mini Review
Ahmed A Khalifa FRCS* View abstract
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ShareTotal knee arthroplasty (TKA) considered to be one of the most common orthopedic surgical procedures performed worldwide. Anesthesia techniques had been developed as part of the development of the TKA surgical techniques over the past decades. Regional anesthesia started to take the upper hand as the dominant form of anesthesia from the general anesthesia which was considered as the standard practice in the past. It had been shown in many studies the probability of reducing intra-operative blood loss, length of hospital stays, patient outcomes and mortality rates when regional anesthesia was used instead of general anesthesia...... ReadMore
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Review Article
Saloua Khalfaoui* View abstract
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ShareThe pain of the shoulder at the hemiplegic is one of the main complications arisen post-stroke. The causes are multiple and in most of the cases, they are associated with pre-existent or added risk factors; where from the interest of a premature diagnostic coverage with implementation of the means of prevention and curative treatment to favor the neurological recovery...... ReadMore
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Case Report
Aamir Siddiqui* View abstract
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ShareVitamin B12 deficiency usually mimics megaloblastic anemia, pancytopenia, neurological symptoms and, rarely, hemolytic anemia. This report describes a case with symptoms of apathy and findings suggestive of severe hemolytic anemia, diagnosed with vitamin B12 deficiency. Haemolysis is a rare hematological finding in cases of B12 deficiency, and descriptions of a nutritional vitamin B12 deficiency, without evidence of pernicious anaemia, causing haemolysis, are even scarcer, and this paper was intended to draw physicians� attention to this rare form of presentation...... ReadMore
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Research Article
Alaa Ali M Elzohry* View abstract
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ShareBackground: Major abdominal surgeries still the main line of treatment for upper abdominal malignancies and these surgeries induce severe postoperative pain with different types either somatic or visceral. If such pain not controlled, may cause various organ dysfunctions and prolong both hospital and ICU stay. So, an appropriate pain therapy to those patients with least complications must be applicated.Objective: To compare analgesic efficacy of intraperitoneal irrigation of fentanyl added to levo-bupivacaine versus patient controlled intravenous analgesia in patients undergoing major abdominal cancer surgeries. Methods: 120 patients (ASA II-III) of either sex were scheduled for elective upper abdominal cancer surgeries. Patients were randomly allocated into three groups (40 patients each), to receive: post-operative PC..... ReadMore
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Review Article
Siccandar Jeelani* View abstract
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ShareCorticosteroids are used in the management of Oral and maxillofacial lesions because of their anti-inflammatory and immunosuppressive effects. The anti-inflammatory and immunosuppressive effects of steroids reflect them as the magic drug of choice. However, the potential risks have to be taken into judicious consideration before prescribing corticosteroids because they are a double-edged sword...... ReadMore
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Case Report
Juan F Martin Lazaro*, Marc Brown, Emily Gould, Johann Grundlingh, Michal Brys Ieva Norkiene, Joaquim Cevallos, James Napier, Khyati Lad, Jacek Jablonski View abstract
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ShareRemoval of serum toxins using haemofiltration with human albumin has been demonstrated to be a useful option for the treatment of a patient following the ingestion of unknown substance. Here, a case is described in which a patient presented with symptoms of neuroleptic malignant syndrome after ingesting an unknown Nigerian herbal remedy. Albumin enhanced continuous veno-venous haemodialysis has been previously used for intoxications. When combining continuous renal replacement therapy with albumin, the toxins are bound to the larger molecule which prevents the toxins moving through the filter; allowing for clearance from the blood. We suggest that Intensive Care Units should consider basic tools, such as detox haemofiltration when an unknown poison is suspected..... ReadMore
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Opinion
Seun Ayoade* View abstract
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ShareThe cellular dust hypothesis states that all life (including human life) and the physical universe/entire cosmos came to be as a result of the activities/chemical reactions carried out by indestructible microscopic (maximum size 500 nanometre) entities called microzymas [1]. Discovered in the mid-1800s, alternative terms for macerozymes include cellular dust, protits, bions, scintillating corpuscles, siphonospora polymorpha etc [2]. These microzymas are found in all living things and continue to exist when living things perish. They are immortal and are considered to be the basic unit of life/living thing according to the Terrain and Germ Terrain Duality theories of disease [3]...... ReadMore
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Editorial
Igor Klepikov* View abstract
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ShareThe question raised in the title of this letter is a natural consequence of the findings and conclusions that have been growing steadily in recent years regarding the results of treatment for acute pneumonia (АР). If you look at the publications of recent years in this field of medicine, it turns out that one of the main obstacles to progress in improving the results of treatment of this disease is the lack of appropriate methods for determining the pathogen. Thus, the lack of timely diagnostic information about the etiology of the disease excludes the possibility of targeted antibiotic therapy. In recent years, such regrets have become more and more relevant, playing the role of the main explanation for treatment failures..... ReadMore
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Research Article
Naomi Ujino, Junko Nakahira*, Shoko Nakano, Toshiyuki Sawai and Toshiaki Minami View abstract
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ShareBackground: Over-insertion of a pulmonary artery catheter (PAC) can cause serious complications, such as pulmonary embolism and pulmonary artery rupture. Careful management is essential. Methods: This study investigated relationships between patient parameters and appropriate PAC insertion length. A function on the chest X-ray display was used to measure the curve. In Study 1, we investigated concordance using intraclass concordance coincidence (ICC) between recorded insertion length of the PAC and actual inserted length. We reviewed recorded insertion data from patients� anesthesia records and measured actual inserted length. In Study 2, we measured and estimated the appropriate insertion length using chest X-rays taken just after surgery. Multiple logistic regression was performed to investigate relati..... ReadMore
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