Topical “Medistick” Of Antifungal, the New Future of Drug-Cosmetic

Parth Shah and Bhupendra G Prajapati*

Received: March 14, 2018;   Published: March 20, 2018

DOI: 10.32474/RRHOAJ.2018.01.000114

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Abstract

Main aim of developing medicated stick is to cure topical problems and also for beauty purpose by natural ingredients. This formulation is combination of both branches (drug-cosmetic).The drug used in the formulation is Ketoconazole which is used for antifungal therapy. Pre formulation studies revealed that API and excipients were found to be compatible. For the formulation of medstick self emulsify drug delivery system was used. Take a solubility profile then three basic preliminary trials taken for making SEDDS. Optimize the SEDDS. This selection is done by concentration of bees wax, concentration of carnauba wax, concentration of castor oil and concentration of Isopropyl myristate. Evaluation test like breaking load test, softening point, permeability, melting point and antifungal activity etc was performed on the finalized formulation.

Keywords: Ketoconazole; Self emulsifying drug delivery system (SEDDS); Medicated stick; Fungal diseases; Beautification; Excipients; Optimization; Evaluation; Stability

Abstract| Cosmetics| Cosmeceuticals| Introduction| Material and Method| Method| Conclusion| References|