email   Email Us: phone   Call Us: +1 (914) 407-6109   57 West 57th Street, 3rd floor, New York - NY 10019, USA

Lupine Publishers Group

Lupine Publishers

ISSN: 2637-6679

Research and Reviews on Healthcare: Open Access Journal

Research Article(ISSN: 2637-6679)

Topical “Medistick” Of Antifungal, the New Future of Drug-Cosmetic

Volume 1 - Issue 3

Parth Shah and Bhupendra G Prajapati*

  • Author Information Open or Close
    • Department of Pharmaceutical Technology, Ganpat University, India

    *Corresponding author: Bhupendra G Prajapati, Associate Professor, Department of Pharmaceutical Technology, Ganpat University, Ganpat Vidhyanagar, Mehsana, Gujarat-384012, India

Received: March 14, 2018;   Published: March 20, 2018

DOI: 10.32474/RRHOAJ.2018.01.000114

Full Text PDF

To view the Full Article   Peer-reviewed Article PDF


Main aim of developing medicated stick is to cure topical problems and also for beauty purpose by natural ingredients. This formulation is combination of both branches (drug-cosmetic).The drug used in the formulation is Ketoconazole which is used for antifungal therapy. Pre formulation studies revealed that API and excipients were found to be compatible. For the formulation of medstick self emulsify drug delivery system was used. Take a solubility profile then three basic preliminary trials taken for making SEDDS. Optimize the SEDDS. This selection is done by concentration of bees wax, concentration of carnauba wax, concentration of castor oil and concentration of Isopropyl myristate. Evaluation test like breaking load test, softening point, permeability, melting point and antifungal activity etc was performed on the finalized formulation.

Keywords: Ketoconazole; Self emulsifying drug delivery system (SEDDS); Medicated stick; Fungal diseases; Beautification; Excipients; Optimization; Evaluation; Stability

Abstract| Cosmetics| Cosmeceuticals| Introduction| Material and Method| Method| Conclusion| References|


Online Submission System

Drag and drop files here


Browse Files
( For multiple files submission, zip them in a single file to submit. For file zipping software Download )