Evaluation of the Anti-Inflammatory Activity of Semi
-Purified Glycoside Extracted from the Leaves of
Plumeriarubra (Kalachuchi)
Volume 1 - Issue 1
Betina Lois Laine C Baltazar, Lyra Mae D Baluyut, Mark Ian T Ibay, Rikki Mae M Punzalan, Lois C Reyes and Renato I
Dalmacio*
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- College of Pharmacy, Research and Development and Innovation Center, Philippines
*Corresponding author:
Renato I Dalmacio, Our Lady of Fatima University, Philippines City of San Fernando, Pampanga, Philippines
Received: February 03, 2018; Published: February 07, 2018
DOI: 10.32474/RRHOAJ.2018.01.000104
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Abstract
The researchers focused on skin inflammation. An inflammation
is a biological response of the body aiming to remove the harmful
stimuli that affects a part of our body. Based on visual observation,
the ancients characterized inflammation by five cardinal signs;
heat (calor) is caused by the increased movement of blood through
dilated vessels into the environmentally cooled extremities, also
resulting on the increased redness (rubor), swelling (tumor) is the
result of increased passage of fluid from dilated and permeable
blood vessels into the surrounding tissues, infiltration of cells
into the damaged area, and in prolonged inflammatory responses
deposition of connective tissue, pain (dolor) is due to the direct
effects of mediators, either from initial damage or that resulting
from the inflammatory response itself, and the stretching of sensory
nerves due to oedema and loss of function (functiolaesa) refers to
either simple loss of mobility in a joint. (Punchard N.A., Whelan C.J.,
Adcock I., 2004)[1-3].
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