email   Email Us: phone   Call Us: +1 (914) 407-6109   57 West 57th Street, 3rd floor, New York - NY 10019, USA

Lupine Publishers Group

Lupine Publishers

  Submit Manuscript

ISSN: 2637-6679

Research and Reviews on Healthcare: Open Access Journal

Research Article(ISSN: 2637-6679)

A Rare Case of Hemophagocytic Lymphohistiocytosis in a Young Adult Male with Mediastinal Mixed Germ Cell Tumor

Volume 4 - Issue 5

Onyedika Umeanaeto MD1*, M Nawar Hakim MD2, Jesus Diaz MD3, Charlene Ofosu MD3 and Sumit Gaur MD1

  • Author Information Open or Close
    • 1Department of Internal Medicine, Paul L Foster School of Medicine, USA
    • 2Department of Pathology, , Paul L Foster School of Medicine, USA
    • 3Department of Radiology, Paul L Foster School of Medicine, USA

    *Corresponding author: Onyedika Umeanaeto MD, Resident Physician, Department of Internal Medicine TTUHSC-El Paso. 4800 Alberta Avenue, El Paso, TX 79905. USA

Received: February 24, 2020;   Published: March 04, 2020

DOI: 10.32474/RRHOAJ.2020.04.000200

Full Text PDF

To view the Full Article   Peer-reviewed Article PDF


Hemophagocytic lymphohistiocytosis (HLH) is a life threatening and fatal medical condition which usually results in death in patients that are affected even with adequate and proper medical care. Due to how uncommon this condition is, delay in diagnosis is most often the major determinant of prognosis since in many cases patient are diagnosed late in their hospital stay. It most frequently affects infants from birth to 18 months of age, but the disease is also observed in children and adults of all ages. HLH can occur as a familial or sporadic disorder, and it can be triggered by a variety of events that disrupt immune homeostasis. Infection is a common trigger both in those with a genetic predisposition and in sporadic cases.

Introduction| Case Presentation| Discussion| References|