A Review on Nerve Conduction Studies

Volume 1 - Issue 3

Mehrnaz Moattari¹, Farahnaz Moattari², Gholamreza Kaka³ and Homa Mohseni Kouchesfahani¹*

Received: September 14, 2018;   Published: September 21, 2018

DOI: 10.32474/SJPBS.2018.01.000115

Full Text PDF

To view the Full Article   Peer-reviewed Article PDF

Abstract

Electrophysiological measurements are indispensable tool for investigating the functional integrity of peripheral nerves in both clinical and laboratory environments. Nerve conduction study is a property of both the axons and myelin sheath. The nerve conduction velocity is highly dependent on rapid signal propagation enabled by myelination. The compound motor action potential (CMAP) which correlates with the number of functional axons is an indicator for axonal damage when significantly reduced. Because nerve conduction velocity (NCV) is sensitive to both myelin sheath and axonal changes, it is an excellent measure of the function of the peripheral nervous system. Nerve conduction studies may be diagnostically helpful in patients suspected of having almost any peripheral nervous system disorder including disorders of nerve roots, peripheral nerves, muscle and neuromuscular junction. Cranial nerves and spinal cord function may also be assessed. Here, we mentioned the components and properties of nerve conduction study.

Keywords: Amplitude; Compound Motor Action Potential; Late Response; Latency; Nerve Conduction Study; Nerve Conduction Velocity; Sensory Nerve Action Potential

Abstract| Introduction | Temporal Dispersion & Phase Cancellation | Antidromic Sensory Study | Orthodromic Sensory Study | Late Response | Interpretation of Nerve Conductions | Physiologic Variation among Different Nerve Segments | Conclusion | References |