Gorlin Goltz Syndrome: Report of A Clinical Case with no
Genetic Background
Volume 6 - Issue 2
Gabriela Elizabeth Gómez Cárdenas1, Cristóbal Landa Román2* and Francisco Javier Gómez Pamatz3
- 1Student, Faculty of Dentistry, Universidad Michoacana de San Nicolás de Hidalgo, Mexico
- 2Master in Public Health, Dental Surgeon, Graduated from Universidad Michoacana De San Nicolas Hidalgo, Private Dental Practice, Mexico
- 3Doctorate in Educational Sciences, Master’s Degree in Psychopedagogy, Maxillofacial Surgeon of the Pediatric Dentistry Service at the
Children’s Hospital of Morelia, Mexico
Received:May 24, 2021 Published: June 04, 2021
*Corresponding author: Cristóbal Landa Román, Dental Surgeon, Graduated from Universidad Michoacana De San Nicolas Hidalgo,
Private Dental Practice, Mexico
DOI: 10.32474/IPDOAJ.2021.06.000233
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Abstract
First described in 1960 by pathologist Robert Gorlin and dermatologist Robert W Goltz of the University of Minnesota, USA, they
provided the basis for the diagnosis of the syndrome, establishing basal cell carcinomas, keratocysts, and skeletal malformations
as the primary criteria for the syndrome. Subsequently, authors such as Evans, Kimonis, and Bree established major and minor
criteria for the correct diagnosis. According to the International Classification of Applied Diseases in Dentistry and Stomatology
(ICD-AO), Gorlin Goltz Syndrome is classified within congenital anomalies and other hamartomatosis. It is caused by a mutation
in chromosome 9q22.3 in the tumor suppressor Patched 1. This work presents the clinical case of a 10-year-old female patient
with a 13x15cm volume increase in the maseterine region on the left side, diagnosed as Gorlin Goltz Syndrome with no hereditary
antecedents.
Keywords:Syndrome; Gorlin-Goltz, Basal Cell carcinoma; Keratocysy; Chromosome 9
Abstract|
Background|
Differential Diagnosis|
Histopathology|
Radiology|
Treatment|
Clinical Case|
Discussion|
Recognition|
Radiology|
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