email   Email Us: info@lupinepublishers.com phone   Call Us: +1 (914) 407-6109   57 West 57th Street, 3rd floor, New York - NY 10019, USA

Lupine Publishers Group

Lupine Publishers

ISSN: 2637-6636

Interventions in Pediatric Dentistry: Open Access Journal

Review Article(ISSN: 2637-6636)

Gorlin Goltz Syndrome: Report of A Clinical Case with no Genetic Background Volume 6 - Issue 2

Gabriela Elizabeth Gómez Cárdenas1, Cristóbal Landa Román2* and Francisco Javier Gómez Pamatz3

  • 1Student, Faculty of Dentistry, Universidad Michoacana de San Nicolás de Hidalgo, Mexico
  • 2Master in Public Health, Dental Surgeon, Graduated from Universidad Michoacana De San Nicolas Hidalgo, Private Dental Practice, Mexico
  • 3Doctorate in Educational Sciences, Master’s Degree in Psychopedagogy, Maxillofacial Surgeon of the Pediatric Dentistry Service at the Children’s Hospital of Morelia, Mexico

Received:May 24, 2021   Published: June 04, 2021

*Corresponding author: Cristóbal Landa Román, Dental Surgeon, Graduated from Universidad Michoacana De San Nicolas Hidalgo, Private Dental Practice, Mexico

DOI: 10.32474/IPDOAJ.2021.06.000233

Fulltext PDF

To view the Full Article   Peer-reviewed Article PDF

Abstract

First described in 1960 by pathologist Robert Gorlin and dermatologist Robert W Goltz of the University of Minnesota, USA, they provided the basis for the diagnosis of the syndrome, establishing basal cell carcinomas, keratocysts, and skeletal malformations as the primary criteria for the syndrome. Subsequently, authors such as Evans, Kimonis, and Bree established major and minor criteria for the correct diagnosis. According to the International Classification of Applied Diseases in Dentistry and Stomatology (ICD-AO), Gorlin Goltz Syndrome is classified within congenital anomalies and other hamartomatosis. It is caused by a mutation in chromosome 9q22.3 in the tumor suppressor Patched 1. This work presents the clinical case of a 10-year-old female patient with a 13x15cm volume increase in the maseterine region on the left side, diagnosed as Gorlin Goltz Syndrome with no hereditary antecedents.

Keywords:Syndrome; Gorlin-Goltz, Basal Cell carcinoma; Keratocysy; Chromosome 9

Abstract| Background| Differential Diagnosis| Histopathology| Radiology| Treatment| Clinical Case| Discussion| Recognition| Radiology| References|

Close

Online Submission System

Drag and drop files here

or

Browse Files
( For multiple files submission, zip them in a single file to submit. For file zipping software Download )