The Role of Undifferentiated Connective Tissue Dysplasia in the Development and Clinic of Non-Traumatic Subarachnoid Hemorrhage Volume 4 - Issue 3

Shchepankevich LA^1,2*, Petrova EV², Gribacheva IA², Popova TF², Novikova EG¹ and Pervuninskaya MA¹

• ¹Federal State Budgetary Scientific Institution, Federal Research Center of Fundamental and Translational Medicine, Novosibirsk, Russia
• ²Neurology Department, Federal State Budgetary Educational Institution, Novosibirsk State Medical University, Novosibirsk, Russia

Received: September 01, 2020;   Published: September 09, 2020

Corresponding author: Shchepankevich LA, Neurology Department, Federal State Budgetary Educational Institution, Novosibirsk State Medical University, Novosibirsk, Russia

DOI: 10.32474/OJNBD.2020.04.000189

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Abstract

Objectives: Assessments of the clinical manifestations of undifferentiated connective tissue dysplasia (UCTD) can help for early diagnosis with the definition of the characteristics and prognosis of the subarachnoid hemorrhage (SAH) with the definition of further correct management and preventive measures.

Materials and Methods: we study a group of patients with non-traumatic subarachnoid hemorrhage (n=165) who were admitted at the Stroke Unit #1 in Novosibirsk (Russia) from 2013 till 2017 years. The dysplastic structure of the cerebral vessels and the peculiarities of the craniovertebral junction were assessed by CT angiography, USDG, R-graphy of the skull, and brain MRI.

Results: The evaluation of the clinical, constitutional anatomical, radiology and ultrasound parameters showed that determine the development of non-traumatic subarachnoid hemorrhage of aneurysmal origin in young people are combined with stigmas of undifferentiated connective tissue dysplasia.

Conclusion: The analysis of clinical features of patients with non-traumatic subarachnoid hemorrhage and undifferentiated connective tissue dysplasia provides information that finding of stigma of dysembryogenesis can be early signals of cerebral vessels pathology.

Keywords: Undifferentiated Connective Tissue Dysplasia; Non-Traumatic Subarachnoid Hemorrhage

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