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ISSN: 2637-6628

Online Journal of Neurology and Brain Disorders

Mini Review(ISSN: 2637-6628)

Systematic Review of a Series of Home-Grown Studies Concerning Thymoleptics Benefit Re Deficit Syndrome of Schizophrenia Volume 5 - Issue 2

Saeed Shoja Shafti*

  • Full Professor of Psychiatry, University of Social Welfare and Rehabilitation Sciences (USWR), Razi Psychiatric Hospital, Iran

Received: February 08, 2021   Published:February 22, 2021

Corresponding author: Saeed Shoja Shafti, Full Professor of Psychiatry, University of Social Welfare and Rehabilitation Sciences (USWR), Razi Psychiatric Hospital, Iran

DOI: 10.32474/OJNBD.2021.05.000208

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Abstract

Drug addiction is a chronic, relapsing brain disorder. Pathological neuroplasticity changes in the brain areas involved in cognition, memory and reward lead to intensely psychological dependence on abused drugs in addicts. The key to drug addiction treatment is how to prevent the high relapse rate after withdrawal. Mammalian Target of Rapamycin (mTOR) signaling pathway exists widely in vivo and has variously complex physiological function, which can regulate drug memory by affecting synaptic plasticity. This mini-review discussed the role and research progress of the mTOR signaling pathway in drug memory.

Abstract| Introduction| Methods| Statistical Analysis| Results| Discussion| Conclusion| References|

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