Distribution of Multilayered Fiber Terminals in
the Human Cerebellar Cortex. Visualization by
Immunohistochemistry for Histamine
Volume 2 - Issue 3
Anna Rizzi, Matteo Saccia and Vincenzo Benagiano*
-
Author Information
Open or Close
- Department of Basic Medical Science Neuroscience and Sensory Organs, University of Bari, Italy
*Corresponding author:
Sergei Pakriev, Department of Psychiatry, Izhevsk State Medical Academy, Izhevsk, Russia
Received: February 12, 2019 ; Published: February 21, 2019
DOI: 10.32474/OJNBD.2019.02.000139
Full Text
PDF
To view the Full Article Peer-reviewed Article PDF
Abstract
The distribution of histamine in the human cerebellar cortex was studied by light microscope immunohistochemistry using a
rabbit polyclonal antibody anti-histamine. In all layers of the cerebellar cortex, were revealed punctate immunoreactive elements
related to putative histaminergic nerve terminals. These findings provide insights into the existence of a histaminergic system in the
human cerebellar cortex, presumably involved in the cerebrocerebellar circuit, the feedback circuit through which the cerebellum
is widely connected with the neocortex and the hypothalamus and intervene in the regulation of motor and non-motor functions.
Keywords: Cerebrocerebellar Circuit; Hypothalamus; Cerebellum; Multilayered Fibers; Histamine
Abstract|
Introduction|
Material and Methods|
Results|
Discussion|
References|