MS Al-Ajely* and I M Shaban

DOI : 10.32474/ANOAJ.2019.01.000125

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It was known that nearly 65% of anti-cancer drugs granted market approved by FDA between 210-1015 are heterocyclic compounds and about 95% of heterocyclic compounds are drugs. Heterocyclic compounds containing nitrogen atoms in their structures (nitrogen based)were also proved by FDA during the above period that they form two third of cancer drugs. There are many corresponding reviews associated with the impact and usage of different heterocyclic compounds as anti- platelet, antihypertensions and a lot of biological and medicinal applications. So according to the importance of heterocyclic compounds in therapeutic and a variety of pharmaceutical, medicinal applications which attracts attentions of many researchers on synthesizing new compounds of this class. We are here synthesizing some new nitrogen containing heterocyclic compounds, Pip..... ReadMore

Tass Holmes*

DOI : 10.32474/ANOAJ.2019.01.000124

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Nanotechnology employs substances comprising particles of one to 100 nanometres (nm) in size [1,2], in other words, finely powdered ‘dusts’. These are generally manufactured, and do not occur in nature, although natural materials of small particle size are included in the definition. Nanomaterials reputedly display ‘unique phenomena’, offering economic potential through manipulation of nanoparticles for novel applications [3]. Hence nanotechnology requires study and ‘fine-tuning’ of atomic, molecular and macro-molecular materials, whose properties may vary from those manifested by materials in ‘bulk’ dimensions [4]. These aims imply existing (and growing) expertise regarding the required ‘fine-tuning’ processes and suggest that manipulating nano-dusts will create benefits for society, in technological and, for instance..... ReadMore

Pritam Jain S*, Vrushali Patil A, Ansari Shoaib Ahmed Ayaz Ahmed, Champalal Pawara T and Sanjay Surana J

DOI : 10.32474/ANOAJ.2019.01.000123

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Nicardipine (NCD) is the dihydropyridine class of calcium channel blockers. This study exits a concise review of analytical methods for the quantification of NCD in pharmaceutical preparations and biological fluids. NCD accessible single or in combination with added drugs in pharmaceutical matrices with many drugs like nifedipine, isradipine, veramipril, amlodipine and Aliskiren. They include numerous analytical techniques defined in this study for NCD were high-performance liquid chromatography (HPLC), UV-spectrophotometry, spectrofluorometry, electrochemical methods and liquid chromatography-mass spectroscopy (LCMS). The concise review explains the percentage utilization of the various approaches for analysis of NCD...... ReadMore

Ahmadov IS*, Ramazanov MA, Eyvazova GM, Huseynli SZ and Aliyeva ST

DOI : 10.32474/ANOAJ.2019.01.000122

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This research about on the formation of silver nanoparticles (AgNPs) in extract of Scutellaria Baicalensis roots. Comprehensive analyzes were carried out and the characteristics of these nanoparticles, which can be used in medical practices and environmental cleaning problems. The roots extracts of Scutellaria Baicalensis advocates as reductant and stabilizer. The first proof of the formation of AgNPs is the change of color of solution AgNO3 which was added root extract. Then by UV-Vis spectroscopy identificated the absorption peak of AgNPs at 414nm –461nm interval. Other characterization of AgNPs received with SEM analysis, From SEM pictures it is clear that the AgNPs have a spherical form, with size ranging from 7.12nm to 18.8nm. An average size of AgNPs are 11.35nm. By FTIR analysis of AgNPs was established the stru..... ReadMore

Dina S Ahmed, Hadeel Adil and Emad Yousif *

DOI : 10.32474/ANOAJ.2018.01.000121

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Nanomaterials and their derived sub-groups are emerging into the advanced materials field due to their high free porous volume, structural regularity, robustness, hydrothermal stability, and functional variety. They present high gas uptake capacities and presence of stabilized active functions in the framework. A significant technical challenge has been recognized as the development of a viable method to efficiently trap hydrogen, methane and carbon dioxide gas molecules in a confined space for various applications...... ReadMore

Madiha Batool*, Zahid Qureshi and Aliya Basir

DOI : 10.32474/ANOAJ.2018.01.000120

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Green synthesis for nanoparticles using microorganisms, enzymes, and plants leaf or plant extracts have been indicated as possible ecofriendly preferences to chemical and physical methods. In this paper, we report the synthesis of zinc oxide particles by green method. Highly stable and hexagonal zinc oxide nanoparticles were produced by using zinc nitrate and green tea leaf extract. Structural, morphological and optical properties of the synthesized nanoparticles have been characterized by using UV–Vis spectrophotometer, FTIR, SEM, and XRD analysis. The synthesis of nanoparticles of zinc oxide was observed by the color changing of the chemical solution. Powder X-ray diffraction and SEM analysis revealed the synthesis of both Zn and ZnO nanoparticles with average particle size of..... ReadMore

Madiha Batool , Zahid Qureshi , Nida Mehboob and Abdul Salam Shah

DOI : 10.32474/ANOAJ.2018.01.000119

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The biosynthesis of nanoparticles put forward a cost-free and eco-friendly method for the synthesis of nanoparticles. In this paper degradation of Malachite green has been carried out using Copper nanoparticles synthesized by Aloe Barbadensis leaf extracts. The green synthesis of the copper nanoparticles has been carried out using an aqueous solution of copper sulphate and extract of Aloe Barbadensis. The colour change of the reaction mixture containing 1mm copper sulphate has been observed from deep blue to colourless and then brick red to dark red indicating the formation of copper nanoparticles. For the characterization of CuO nanoparticles, Ultraviolet (UV), Infrared (IR), X-ray Diffraction (XRD), and Scanning Electron Microscopy (SEM) have been used. The experimental analysis has rev..... ReadMore

Yunusov Khaydar Ergashovich*, Sarymsakov Abdushkur Abdukhalilovich and Rashidova Sayora Sharaphovna

DOI : 10.32474/ANOAJ.2018.01.000118

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Silver nanoparticles stabilized in a solution of sodium carboxymethylcellulose (Na-CMC) with a degree of substitution of 0.65-0.85 and degree of polymerization of 200-600 were synthesized. Physical, chemical properties, and antimicrobial activity of films prepared from sodium carboxymethylcellulose solutions containing silver nanoparticles were studied. The shapes, quantities, and sizes of the silver nanoparticles occurring in the sodium carboxymethylcellulose films were determined by atomic force microscopy and UV - spectroscopy. The shape, size, and quantity of silver nanoparticles determine their biological activity. At increase of the silver nanoparticle sizes of 5 up to 25 nm was found to enhance the microbicidal activitiy of the carboxymethylcellulose films...... ReadMore

Loreana Molero , Luissanyi Campos , Luis Sosa , Yuanbing Mao , Nancy Flores , Efren Delgado and Karen Lozano

DOI : 10.32474/ANOAJ.2018.01.000117

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Glandless cotton seed meal (GCSM) extracted from cotton is composed of nearly 50 percent protein. For about every 100kg of cotton fiber produced the cotton plant yields approximately 160kg of cottonseed. GCSM presents a unique opportunity to be used in the food industry. In this study, GCSM based polymer composite edible fine fibers were successfully produced using pullulan as the polymeric base. GCSM solutions were developed and spun as fine fibers using a centrifugal spinning technology. A synergistic approach among fiber output and fiber diameter was pursued by modifying angular velocity and concentration of pullulan and GCSM within an aqueous solution. The developed fibers show average fiber diameters of 720nm with a standard deviation of 200nm. Thermo-physical analysis was conducted. The opportunity to develop GCSM fine fiber ma..... ReadMore

Jayshree Ramkumar

DOI : 10.32474/ANOAJ.2018.01.000116

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The rapid pace of industrialization and its resulting by-products have affected the environment by producing hazardous wastes and poisonous gas fumes and smokes, which have been released to the environment. Conventional technologies have been used to treat all types of organic and toxic waste by sorption, biological oxidation, chemical oxidation and incineration. Super-critical water oxidation (SCWO) is an emerging technique for treatment of organic waste. Nanomaterials find extensive applications [1] and their use in environmental remediation is becoming quite attractive. The removal of pollutants from the environment is based on the reactivity of the nanomaterial used and the pollutants may either be sorbed or degraded. The advantages of using nanosor..... ReadMore

Emad Yousif

DOI : 10.32474/ANOAJ.2018.01.000115

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Carbon nanotubes (CNTs) have generated huge activity in most areas of science and engineering due to their remarkable physical and chemical properties. No previous materials have displayed the combination of superlative mechanical, thermal and electronic properties attributed to them. These roperties make nanotubes ideal, not only for a wide range of applications but as a test bed for fundamental science. This review highlighted some of the properties of these nanotubes and also their role as supports materials in enhance of photocatalytic activity of nanocrystals for removal of contaminants..... ReadMore

Farouk S Nas , Muhammad Ali and Aminu Muhammad A

DOI : 10.32474/ANOAJ.2018.01.000114

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Bacterial strains resistant to the antibiotics now in use have becomes serious public health problems that increases the need to develop new bactericidal materials. Consequently, there is a strong demand for developing novel strategies and new materials that can cope with these problems. The emergence of anotechnology has created many new antimicrobial options. The small size of the nanoparticles is very suitable for carrying out antimicrobial biological operations. Metals such as silver, zinc, copper and iron nanoparticle types have shown tremendous potential as bactericidal and fungicidal elements, demonstrating their potential as efficient antibiotic reagents in wound care and related medical issues. These nanomaterials displayed antimicrobial activity against numerous pathogenic viral and bacterial s..... ReadMore

Apurba K Das* and Rohit G Jadhav

DOI : 10.32474/ANOAJ.2018.01.000113

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In the current era of research and development, nanotechnology and additive manufacturing play a key role in the industry as well as in the healthcare applications. In order to explore medicinal applications, researchers focus on the design and synthesis of biocompatible nanoparticles and nanomaterials. olecular self-assembly is a powerful approach for the fabrication of supramolecular functional materials. Self-assembly offers the integration of nanotechnology with the additive manufacturing for the fabrication of three dimensional (3D) printed objects. The cross-linked peptide hydrogels are gaining attention as potential bio-ink for the 3D bio-fabrication. The current article focuses on the scope of the rintable peptide containing hydrogels as bio-ink in the fields of nanomedicine, drug ..... ReadMore

Subodh Kumar, Phulen Sarma, Rahul Soloman Singh, Dibbanti Harikrishna Reddy, Sukhjinder Singh, Ashutosh Singh and Bikash Medhi

DOI : 10.32474/ANOAJ.2018.01.000112

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Targeting cancer using nanomedicine is not a new concept. Earlier focus was on targeted therapy and then concept came of combinational therapy. Along with the use of combinational therapies, Pre-selection screening of the patients using molecular approach is equally important to achieve the maximum benefit to the cancer patients..... ReadMore

R Kandasamy*, Mohammed Mahdi Fayyadh and Radiah Mohammad

DOI : 10.32474/ANOAJ.2018.01.000110

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Energy is an extensive view for industrial advancement. Solar thermal energy is designed by light and heat which is radiated by the sun, in the form of electromagnetic radiation. Solar energy is the highest promptly and sufficiently applicable authority of green energy. Impact of nanoparticle shapes on the Hiemenz nano fluid (water based Cu, Al2O3 and SWCNTs) flow over a porous wedge surface in view of solar radiation energy has been analyzed. The three classical form of nanoparticle shapes are registered into report, i.e. sphere , cylinder and laminar . Nanoparticles in the water based Cu, Al2O3 and SWCNTs have been advanced as a means to boost solar collector energy through explicit absorption of the entering solar energy. The controlling partial differential equations (PDEs) are remodeled into ordinary differential equations (ODEs) b..... ReadMore

Madiha batool*, Asma Khalid and Huma Raza

DOI : 10.32474/ANOAJ.2018.01.000109

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This investigation was carried out to determine the pH, levels of caffeine contents in five soft drinks and four energy drinks available in local market of Pakistan. pH were measured by pH meter. Quantitative estimation of caffeine was performed by a simple and fast standard UV spectrophotometric method (Perkin Elmer lambda 35 UV/Vis spectrometer) using carbon tetrachloride as the extracting solvent at 270nm wave length. The minimum caffeine level of soft drinks was observed in Brand-3 (10.69 mg/serving), while Brand-5 showed the highest caffeine content (42.17mg/serving) showing a range from 10.6 to 42.17mg/serving. The levels of caffeine in all energy drink samples are well below the maximum allowable limits set by the food regulatory bodies, except E2. The E2 has greater calculated concentration then the labeled concentration .The mi..... ReadMore

Madiha Batool* and Nida Mehboob

DOI : 10.32474/ANOAJ.2018.01.000108

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he present study was aimed to account a green synthesis of copper nanoparticle is by interaction of leaf extract and copper salt. The bio-synthesis of nanoparticles put forward a cost free and eco-friendly method of nanoparticle synthesis. Copper nanoparticles were synthesized by using aqueous solution of copper sulphate and extract of Aloe barbadensis. The prepared leaf extract was observed when 1mM copper sulphate solution is added in it. Color change of the reaction mixture was observed from deep blue to colorless and then to brick red and dark red indicating the formation of copper nanoparticles. The synthesized CuO NPs was haracterized by using different technique such as UV, IR, XRD, and SEM. ward a cost-free and environmentally suitable method of nanoparticle synthesis. Synthesized CuO nanoparticles with average particle size of 6..... ReadMore

Force Tefo Thema*

DOI : 10.32474/ANOAJ.2018.01.000106

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γ-ray radiation was used to reduce graphene oxide thin films to partially reduced graphene oxide films at ambient conditions. Micro-Raman spectroscopy showed that irradiation of GO with γ-rays did not change the structure of graphene. The γ-rays are only active on the oxygen functional groups bonds because they are short and highly energized wavelengths. γ-rays penetrate the C-C lattice isotropically hence sustaining the graphene layer structure. This results in transparent and intact r-GO thin films with no structural defects. The defects on the structure would result to the opaqueness of the C-C lattice hence compromising the transparency of the material. The Scanning electron microscopy, Transmission Scanning electron, Fourier transform infrared and Raman spectrometry are presented...... ReadMore

Madiha Batool*, Khuram Shahzad Ahmad*, Zahidqureshi, Nida Mahboob and Nimra

DOI : 10.32474/ANOAJ.2018.01.000107

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Metals like lead, copper, cadmium dispersed in environment. Heavy metals considered toxic. They have adverse and acute after effects on humans. These metals although have beneficial effect but hazards are pronounced. Level of heavy metals is increasing due to rapid industrialization and pollution. Toxicity of metals causes diseases and health issues among people. It is complicated to measure possible health risk of occupational persons. So detection of these metals in blood is important issue. Even at low amount intake of trace element can lead to health problems among people. Blood is directly influenced by toxicity when inhaled these metals from environment where existence of heavy metal is high. This presently, initiate to work on scientific detection of metals effect on human and health assessment. From study metals copper, cadmium, l..... ReadMore

Damayanthi Dalu*

DOI : 10.32474/ANOAJ.2018.01.000105

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Objective: Leea indica is a well-known plant with numerous pharmacological activities owing to the presence of the active constituents. Inspite of numerous therapeutic uses, efficacy of the plant in treating ulcers is not yet evaluated scientifically. Hence an attempt has been made to evaluate the Antiulcer activity of Leea indica. Methods: The effect of Leea indica methanolic extract (LIME) on gastric ulcer in pylorus ligation-induced and aspirin induced models was studied by employing LIME at 200 mg/kg, 400 mg/kg. In both the models anitidine (40mg/kg) was employed as the standard. Depending on the model, parameters evaluated were total acidity, free acidity, volume and pH of gastric fluid, ulcer score and percent inhibition of ulcer index. Results: Data were analyzed following graph pad instat version 3.0 followed by Dunnets multipl..... ReadMore