Revisiting the Paper “Origin of the Right-Handed Twist of Beta-Sheets of Poly-L-Valine Chains”

Kuo-Chen Chou*

• Gordon Life Science Institute, Boston, United States of America

Received: September 19, 2020;   Published: October 06, 2020

*Corresponding author: Kuo-Chen Chou, Gordon Life Science Institute, Boston, Massachusetts 02478, United States of America

DOI: 10.32474/SJFN.2020.03.000165

Abstract PDF

In this short report, a very important paper in studying the right-handed twist of beta-sheets in proteins is recalled.

Keywords:Energetics; ECEPP; Beta Strands; Handedness; Proteins

About 38 years ago a very important paper with the title “Origin of the right-handed twist of beta-sheets of poly-L-valine chains” [1] was published. Ever since then, this paper has played very important role for investigation into the three-dimensional (3D) structures of proteins [2-20].

1. Chou KC, Scheraga HA (1982) Origin of the right-handed twist of beta-sheets of poly-L-valine chains. Proceedings of the National Academy of Sciences of the United States of America 79(22): 7047-7051.
2. Chou KC, Pottle M, Nemethy G, Ueda Y, Scheraga HA (1982) Structure of beta-sheets: Origin of the right-handed twist and of the increased stability of antiparallel over parallel sheets. J Mol Biol 162(1): 89-112.
3. Chou KC, Nemethy G, Scheraga HA (1983) Energetic approach to packing of a-helices: 1. Equivalent helices. J Phys Chem 87(15): 2869-2881.
4. Chou KC, Nemethy G, Scheraga HA (1983) Role of interchain interactions in the stabilization of right-handed twist of ß-sheets. J Mol Biol 168(2): 389-407.
5. Chou KC, Nemethy G, Scheraga HA (1983) Effects of amino acid composition on the twist and the relative stability of parallel and antiparallel beta-sheets. Biochemistry 22(26): 6213-6221.
6. Chou KC, Nemethy G, Scheraga HA (1984) Energetic approach to packing of a-helices: 2. General treatment of nonequivalent and nonregular helices. Journal of American Chemical Society 106: 3161-3170.
7. Scheraga HA, Chou KC, Nemethy G (1984) Protein strucrure and function, from colloidal to a molecular view. In: Srinivasan R, Sarma RH (Eds.), Carlsberg Research Communications 49: 1-55.
8. Chou KC, Nemethy G, Pottle MS, Scheraga HA (1985) The folding of the twisted beta-sheet in bovine pancreatic trypsin inhibitor. Biochemistry 24(27): 7948-7953.
9. Chou KC, Nemethy G, Rumsey S, Tuttle RW, Scheraga HA (1985) Interactions between an alpha-helix and a beta-sheet: Energetics of alpha/beta packing in proteins. J Mol Biol 186(3): 591-609.
10. Gerritsen M, Chou KC, Nemethy G, Scheraga HA (1985) Energetics of multi-helix interactions in protein folding: Application to myoglobin. Biopolymers 24: 1271-1291.
11. Chou KC, Nemethy G, Rumsey S, TuttleRW, Scheraga HA (1986) Interactions between two beta-sheets: Energetics of beta/beta packing in proteins. J Mol Biol 188(4): 641-649.
12. Chou KC, Maggiora GM, Nemethy G, Scheraga HA (1988) Energetics of the structure of the four-alpha-helix bundle in proteins. Proceedings of the National Academy of Sciences of the United States of America 85: 4295-4299.
13. Chou KC, Nemethy G, Pottle M, Scheraga HA (1989) Energy of stabilization of the right-handed beta-alpha-beta crossover in proteins. J Mol Biol 205(1): 241-249.
14. Chou KC, Heckel A, Nemethy G, Rumsey S, Carlacci L, et al. (1990) Energetics of the structure and chain tilting of antiparallel beta-barrels in proteins. Proteins Struct Funct Genet 8: 14-22.
15. Chou KC, Nemethy G, Scheraga HA (1990) Review: Energetics of interactions of regular structural elements in proteins. Acc Chem Res 23(5): 134-141.
16. Chou KC, Maggiora GM, Scheraga HA (1992) The role of loop-helix interactions in stabilizing four-helix bundle proteins. Proceedings of the National Academy of Sciences of the United States of America 89(16): 7315-7319.
17. Chou KC, Heinrikson RL (1997) Prediction of the tertiary structure of the complement control protein module. J Protein Chem 16(8): 765-773.
18. Chou KC, Jones D, Heinrikson RL (1997) Prediction of the tertiary structure and substrate binding site of caspase-8. FEBS Lett 419: 49-54.
19. Chou KC, Watenpaugh KD, Heinrikson RL (1999) A Model of the complex between cyclin-dependent kinase 5 (Cdk5) and the activation domain of neuronal Cdk5 activator. Biochemical & Biophysical Research Communications (BBRC) 259: 420-428.
20. Chou KC, Tomasselli AG, Heinrikson RL (2000) Prediction of the Tertiary Structure of a Caspase-9/Inhibitor Complex. FEBS Lett 470: 249-256.