Open Access Journal of Oncology and Medicine

Tayyaba saher* and Muhammad Imran Qadir

DOI : 10.32474/OAJOM.2019.02.000145

View abstract PDF Full text

Share

The present study was objected to check the awareness about SARS among scholars of university. The pupil of Bahauddin Zakariya university Multan acted as the subjects for this research. Total of 109 subjects showed consent to be the part of this study. Severe acute respiratory syndrome (SARS) is considered a deadly animal virus which, perhaps originated from bats and then it was spread to other animals. According to a report, the humans were affected by SARS very firstly in 2002 in Guangdong, china......

Rüdiger Hardeland

DOI : 10.32474/OAJOM.2018.02.000144

View abstract PDF Full text

Share

The release of exosomes and ectosomes carrying noncoding RNAs is addressed in the context of cancer, with focus on microRNAs and long noncoding RNAs as well as differences in RNA cargos produced by tumor and nontumor cells. The differential appearance of ncRNAs can be used for diagnostic and prognostic purposes. Beyond these possibilities, the spreading of pathological and beneficial messages deserves particular attention and will gain future importance. Especially the use of exosomes released by cells that overexpress ncRNAs with antitumor properties appears to be a promising strategy......

Misra Jata Shankar

DOI : 10.32474/OAJOM.2018.02.000143

View abstract PDF Full text

Share

Carcinoma cervix is a major health problem faced by Indian women and though its incidence has declined in urban population in recent years but in the rural India where 70% of the people dwell, cervical cancer still remains on top [1]. It is mainly due to illiteracy and ignorance about the factors contributing to the development of cervical cancer......

VK Khanna*

DOI : 10.32474/OAJOM.2018.02.000142

View abstract PDF Full text

Share

Increasing the population and off them living styles effect on the surrounding environment leads to changes in climate with time. In the long run, the climatic change could affect agriculture in several ways such as quantity and quality of crops in terms of productivity, growth rates, photosynthesis and transpiration rates, moisture availability etc. Among the agricultural crops maize is also one of the most important food crops. Predictions suggest that worldwide climate change will reduce maize production this will coincide with a substantial increase in demand for maize due to rising populations. However, selection for climate change adaptation cultivar is difficult due to complex genotype by environment interactions. The broader use of traits from alien species and the m.....

VK Khanna*

DOI : 10.32474/OAJOM.2018.02.000141

View abstract PDF Full text

Share

The impact of climate change on agriculture will be one of the major deciding factors influencing the future food security of mankind on earth. Agriculture is not only sensitive to climate change but, at the same time, is one of the major drivers for climate change. Understanding the weather changes over a period of time and adjusting the management practices towards achieving better harvest is a challenge to the growth of agricultural sector as a whole. The most imminent climatic changes in recent times is the increase in the atmospheric temperatures due to increased levels of greenhouse gases such as carbon dioxide (CO 2 ), methane (CH 4 ), ozone (O 3 ), nitrous oxide (N 2 O) and chloro fluoro carbons (CFCs)......

Bakulesh Khamar*

DOI : 10.32474/OAJOM.2018.02.000140

View abstract PDF Full text

Share

Checkpoint inhibitors have demonstrated efficacy in squamous NSCLC with tolerable toxicity profile. They are used as a monotherapy, in combination with chemotherapy or following chemo-radiotherapy as a first line, second line or consolidation therapy. As a first line, Pembrolizumab improves outcome (PFS) as a monotherapy in patients with PD-L1 expression of ≥ 50% (HR; 0.35). When used with chemotherapy, it improves PFS (HR; 0.56) irrespective of PD-L1 expression level. Nivolumab also improves PFS (HR; 0.62), when used as a second line for those progressing with chemotherapy. Durvalumab improves PFS (HR; 0.68) when used following chemo-radio therapy as a consolidation therapy......

Lale Olcay*

DOI : 10.32474/OAJOM.2018.02.000139

View abstract PDF Full text

Share

We evaluated our thrombosis cases for iron deficiency (ID) or iron deficiency anemia (IDA) retrospectively and reviewed the literature. We established that iron parameters were studied in 17 of 64 patients with thrombosis and 2 of 17 patients had IDA. Case 1 (age 16, female) had occlusions in sigmoid and transverse sinuses and right jugular vein and case 2 (age 15, male) had infarct in right cerebellar hemisphere. While case 1 additionally had mastoiditis, high Factor (F) VIII and PAI 4G/5G polymorphism, case 2 who underwent a recent aortic graft insertion operation for aortic aneurysm had high serum lipids, lipoprotein a, homocysteine, FVIII, d-dimer. Of 54 thrombosis cases with ID/IDA in the literature, cerebral thrombosis made up of 70.4% of all the cases, venous cerebral occlusions comprising 100% and 66% of venous thrombo.....

Obeagu Emmanuel Ifeanyi*

View abstract PDF Full text

Share

Leukaemia is a blood disorder caused by uncontrolled production and release of abnormal blasts cells in the bone marrow and in the circulation. Treatment of leukaemia has been a great challenge and many patients die. The initial methods of treatments were chemotherapy and radiation which target the leukaemic cells. There is a concern on the management of leukaemia patients. This paper was written to enlighten the public on the need to utilize umbilical cord blood in the management of leukaemia patients......

Nathaniel A Parker*

View abstract PDF Full text

Share

Uterine leiomyomas are the most common gynecological tumor in women of reproductive age. These tumors are typically benign entities, but uncommonly transition toward tissues of malignant potential. Rare growth patterns of uterine leiomyomata have been observed which include benign metastasizing leiomyoma (BML), disseminated peritoneal leiomyomatosis (DPL), intravenous leiomyomatosis (IVL), retroperitoneal leiomyomatosis (RPL) and parasitic leiomyoma (PL). Metastasis of uterine fibroids most commonly appear several years after the diagnosis and removal of uterine leiomyomata by hysterectomy. For two women who sought treatment for BML and IVL in our clinic, we retrospectively outlined and evaluated their specific genetic, pathological, and clinical features with the intention to elucidate possible t.....

Adebayo OT*

View abstract PDF Full text

Share

Mobile health care monitoring provides easy assessment of patient’s health status by looking at the changes in vital sign. The health care giver can have access to this data. In this work, a mobile heart rate monitoring system is implemented. In order to detect the heartbeat/pulse. The device works with an android application which receives the data and sends the gotten data to the health care giver. The system makes use of arduino board which functions as a microprocessor. The pulse sensor takes in the pulse readings and the arduino uno micropocesssor converts it to heartbeat via series of programmed instructions on the microprocessor......

Wilson Ib Onuigbo*

View abstract PDF Full text

Share

A 13-year retrospective study of reprint requestors was undertaken with special reference to those from research libraries. It was found that 2.8 percent of the total 2,053 requests were from such librarians. They preponderated in USA, East Germany, Australia, France and Britain. The reason for their requests included Reprint Library acquisitions and exhibition purposes. The librarians tended to ask for reprints from foreign rather than local Journals. All indications are that the reprint has played an important role in scientific communication. In particular, the librarians, who work in research libraries, deserve special scrutiny......

Makki H Fayadh*

View abstract PDF Full text

Share

Colorectal cancer is the fourth (4 th ) common cancer in both sexes, worldwide and is the third most common cancer in men and the second in women. b) In 2012, 1.36 million cases of colorectal cancer occurred and there were 693,881 deaths c) The incidence is increasing under age 50 and it is the second killer cancer in UAE in 2017 [1]. d) According to health authority of Abu Dhabi( HAAD) in a report published in 2012 colon cancer is the 2 nd common cancer and 4 th common cause of cancer deaths in men and 3 rd most common cancer and 2 nd common cause of cancer deaths in women.....

Paul TE Cusack*

View abstract PDF Full text

Share

I was asked to submit a minireview to this journal on oncology. I’ll share an antidotal observation that may prove useful to cancer researchers. I studied hyper-ferritism and Ferric Chloride to see its possible link to schizophrenia. Those results are well published [1,2]. However, I noticed from that research a trend that 12 patients who should have had high hydrogen peroxide (H2O2) also universally had had some form of cancer in their medical history. I wonder if H2O2 is not a carcinogen? Could the H2O2 break down that cell walls leading to cell mutation? I’m not an expert on cancer, nor do I intend to be, but perhaps this clue may lead to further research into to the causes of cancer......

Lawrence M Agius*

View abstract PDF Full text

Share

Dimensional representation of events actively executing the cell cycle dynamics of progression in carcinogenesis allow for aparadoxical emergence of highly permissive elements in the establishment of the mitotic spindle and the separation of chromatids. In such terms, ongoing processes of dissolution of the nuclear membrane betray an essential permissiveness in cell cycling that is paramount constitutional characterization of a process as “passenger” event in defining malignant transformation. In real terms, incremental progression of the cell cycle is specific hallmark for the events that constitutionally permit the system machinery in mitosis to conclusively establish potential re-setting of events as non-re-replication of the cell cycle in the re-emerging G1 phase of mitotic activity.....

VK Khanna*

View abstract PDF Full text

Share

Crossability of various accessions of cowpea on the basis of pollen development and fruit set was studied along with genetic diversity by SSR markers. There was a significant correlation between fruit set and percent viable pollen. In all selfings and the crosses, pollen germination increased from 2 hr to 6 hr after pollination. Pollen germination had a highly significant correlation with fruit set. On selfing, the fruit set was positively correlated with faster pollen tube growth whereas it was not so in the case of crosses. There was a positive correlation between pollen tube growth and fruit set. Thirty six primers were selected to assess genetic diversity of 36 accessions of cowpea and twenty seven primers were found to be polymorphic. The polymorphic primers generated a total of 72 alleles. The number of alleles ranged from 2 to 4 wi.....

Humaid O Al Shamsi * and Sadir Alrawi

View abstract PDF Full text

Share

Cancer is a major health issue around the world, in the United Arab Emirates ( UAE ) it is the 3rd leading cause of death after cardiovascular diseases and injuries, accounting for 10% of all mortalities in the UAE in 2010 [1] and 16% of all mortalities in the Emirate of Abu Dhabi in 2015 [2]. Breast cancer (BC) is the most frequent cancer in females among UAE citizens (32.16%) as well as Non- UAE citizens (41.41%) [3]. Females in the UAE has the tendency to develop BC at least a decade earlier than their counterparts in western countries [3-5]. The UAE government has made strident efforts to promote early cancer detection through different health authorities in the UAE. The Health Authority of Abu Dhabi (The UAE’s largest health district) began to have screening programs for colorectal, breast, and cervical cancers in 2008 [6]......

Lawrence M Agius*

View abstract PDF Full text

Share

Overall tumorigenesis in neurofibromatosis type 1 patients constitutes a series of specific targeting events with a central role enacted by proliferation of fibroblasts and endothelial cells in overproduction of growth factors and cytokines such as transforming growth factor-beta and CXCL12 cytokine. The plexiform neurofibroma well-illustrates dimensions of such cooperative participation within operative fields of the initial Schwann cell proliferation leading in a significant number of patients to malignant transformation of the peripheral nerve sheath tumors. Inclusive directions in operative targeting of Schwann cells or astrocytes are staged performance in the transformation of hyperproliferative induction and constitute further evolutionarily defined incorporation of such systems as endothelial cells. Hyperproliferative cell subset.....

Beatrz Losada Vila*, David Gutiérrez Abad , Beatriz Anton Pascual, Maria Carmen Pantin, Begoña Caballero Perea and Juan Antonio Guerra

View abstract PDF Full text

Share

In 2012, 5.210 new cases of head and neck tumors were estimated in the USA, with an increasing incidence due to tobacco and alcohol habits in the population. A large percentage of the cases debut as a locally advanced disease, so control of the disease is key and we look for the best therapeutic strategy to achieve good survival rates while maintaining quality of life. We present the case of a 60-year-old patient in which our objectives to be presented are the assessment of comorbidity, toxicity and survival......

Dinesh Singh*, Prekshi Chowdhary, Swati and Gopal S

View abstract PDF Full text

Share

Multiple myeloma accounts for <1% of all malignancies and Central nervous system (CNS) manifestation of multiple myeloma (MM) is rare. Multiple myelomais characterized by malignant transformation of plasma cells that produces immunoglobulin chains. The accumulation of plasma cells in bone marrow results in clinical features like anaemia, osteolytic lesions, hypocalcaemia, renal failure and immunodeficiency [1,2]. The involvement of central nervous system is very uncommon in multiple myeloma and it may present early or late during the course of disease. The neurological symptoms can be diffuse headache, persistent vomiting, vertigo, weakness in limbs, urinary incontinence etc. Symptoms can be attributed to spinal cord or nerve root compression, peripheral neuropathies, and uremia [3,4]. Likely risk factors of CNS manifestation are unfavour.....

Ida Micaily MD*, Lakshmi Kolandra DO, Shahrzad Abdollahi MD and Anthony Scarpaci MD

View abstract PDF Full text

Share

Metastatic hormone-receptor and HER-2 positive (triple-positive) breast cancer provides a treatment dilemma for clinicians. The current guidelines offer a variety of options in the first and second line for metastatic breast cancer. A tailored treatment approach is needed for the triple-positive metastatic breast cancer population......