Lupine Publishers Group

DhouhaBacha, Lasaad Gharbi, Ghofrane Talbi, Wael Ferjaoui*, Sahir Omrani and Bouraoui Saadia

DOI : 10.32474/OAJOM.2020.03.000168

View abstract PDF Full text

Share

The ‘’mini method’’ in medical education is characterized by its duration (25-30 min) and the design of its content [1]. It is divided into minimethods which are intended for teaching (MINIt) and for assessment purposes (MINIa). These mini methods are based on several arguments and data taken from cognitive psychology. Otherwise, they are effective pedagogically [2]. However, they are little used in medical education and their description is dismissed and disparate in the literature. The aim of this study is to carry out a comprehensive review on this mini method in order to codify “a new concept in educational pedagogy». Our work try to define, also, its borders with micro method and classic method (also called macro or long method)...... ReadMore

Dani Choufani, Elena Schmidt and Julius Gene Latorre*

DOI : 10.32474/OAJOM.2019.03.000160

View abstract PDF Full text

Share

The association between cancer and thrombosis has been known for a long time, and the majority of the thromboembolic events associated with cancer are usually diagnosed after the cancer being identified [1]. However, a thromboembolic event may precede the identification of a cancer and maybe the first manifestation of the underlying malignancy [2]. Malignant cancers promote hypercoagulable state and increases the risk of thromboembolism. Carcinoma is the most common cause of ischemic stroke associated with malignancy [3] with lung cancers being the most common [1,4] while adenocarcinoma confers a higher risk of recurrent venous thromboembolism (VTE) [5]...... ReadMore

Gurmeet Singh Sarla

DOI : 10.32474/OAJOM.2019.03.000159

View abstract PDF Full text

Share

Background: Beer is one of the most seasoned and most broadly expended alcoholic beverages on the planet and is the third most commonly consumed drink after water and tea world over.Aim: The aim of this review article was to study the health effects of beer consumption and compare the positive effects of consumption of wine, beer and spirits when consumed in moderation.Methods: Literature was searched in the form of epidemiological studies, prospective studies and clinical trials and the health effects of different alcoholic beverages were studied and compared when consumed in moderation. Moderate consumption of beer was defined as non bingeing utilization of 1 beverage for every day in ladies and upto 2 beverages for each day in men.Conclusion: Although alcohol consumption is a two-sided coin, moderate alcohol consu..... ReadMore

Obeagu Emmanuel Ifeanyi*, Okorie Hope M, Obeagu Getrude Uzoma and Anaebo Queen Braxton N

DOI : 10.32474/OAJOM.2019.03.000158

View abstract PDF Full text

Share

Multiple squamous cell carcinomas (MSCCs) in albinos occur mainly due to light melanin and constant exposure to ultraviolet rays of sun light. A study to evaluate changes in haematological parameters was done in albinos with multiple squamous cell carcinomas in a tertiary health institution in Enugu, Nigeria. A total of 40 subjects were recruited for the study comprising 20 subjects each for MSCC and control. About 2ml of venous blood was collected by venepuncture into EDTA anticoagulated containers and Mindray BC-5300 used to measure the haematological parameters. The data were analysed using SPSS version 21 with t-test and significance level set at P<0.05. The results showed increase in ESR (19.80±3.40mm/hr, 6.80±2.33mm/hr, 0.000), WBC (5.91±0.45X109/L,4.65±0.59X109/L,P=0.000), Eosinophils ..... ReadMore

Richard M Fleming*, Matthew R Fleming, Tapan K Chaudhuri and William C Dooley

DOI : 10.32474/OAJOM.2019.03.000157

View abstract PDF Full text

Share

Diagnostic evaluation of chest pain using myocardial perfusion imaging (MPI) is a common method employed to look for coronary artery disease (CAD). The isotopes used in MPI are also useful for imaging cancer, including breast cancer. We present a case where breast cancer was diagnosed using a quantitative method which simultaneously looks for cancer and CAD..... ReadMore

Fatemeh Khatami*, Seyed Mohammad Kazem Aghamir and Maryam Aghaii

DOI : 10.32474/OAJOM.2019.03.000156

View abstract PDF Full text

Share

Ontrary to genetic changes of DNA molecule which change exactly the sequence of DNA and are not reversible, the DNA methylation involves in addition of a methyl group to cytosine nucleotide to control genes expression which is reversible [1,2]. Methylation is unique change that consequence in different gene expression pattern and finally may trigger the onset of diseases like cancer [3]...... ReadMore

Richard M Fleming*, Matthew R Fleming, Tapan K Chaudhuri, Andrew McKusick and William C Dooley

DOI : 10.32474/OAJOM.2019.03.000154

View abstract PDF Full text

Share

Monday 4 February 2019 was yet another World Cancer Day. We celebrated our efforts to find and eradicate cancer without admitting to ourselves that cancer isn’t a single disease, but rather a group of diseases all caused by our bodies responding to the toxic environment we are exposing ourselves to, just as our planet is responding to the toxic wastes we are dumping into it. The question is WHY do our bodies run amok. The answer lies in the same answer to why Global Warming exists...... ReadMore

Richard M Fleming

DOI : 10.32474/OAJOM.2019.03.000153

View abstract PDF Full text

Share

In 1927, Werner Heisenberg [1], published his “Uncertainty principle” which in brief states that it is impos-sible to simultaneously know both the position and momentum of an electron or any other particle with any degree of accuracy or “certainty.” To define the location of an electron required interaction with it. This inter-action would result in movement of the electron and as a result, would move the electron...... ReadMore

Surya Prakash Gautam

DOI : 10.32474/OAJOM.2019.03.000152

View abstract PDF Full text

Share

Carbon Nano materials the king of nonmaterial’s have fascinating nanofamily including buckyballs or buckminsterfullerenes [1], multiwalled carbon nanotubes [2], the single-walled carbon naotubes(SWCNTs) [3], Carbon Nanohorns(CNHs), Carbon nanocones, Carbon nanofibers (CNFs), carbon nanothread, Buckypaper, carbon dots, nanodimons, nanoonions, nanorods, nanoribbons. Also called as powerful particles, CNTs (carbon nanotubes) has thus bloomed over the past decade...... ReadMore

Dr. Gurmeet Singh Sarla*

DOI : 10.32474/OAJOM.2019.03.000151

View abstract PDF Full text

Share

Adequate calcium intake is essential for the maintenance of bone health and the preservation of bone mineral density. The lay person believes that calcium is always good for health. Successful marketing and various clinical practice guidelines have made prescribing calcium supplements a billion dollar market in recent years. The aim of this study was to scan the literature and find out whether calcium supplements should be prescribed to all patients with fractures so as to improve their bone healing or should it be restricted to elderly post- menopausal females who have osteoporotic bones. The inference drawn was that dietary calcium is easier to absorb and may have beneficial effects as compared to calcium supplements and it should be limited to the total daily intake to 1000–1200 mg optimally from dietary sources. Ca..... ReadMore

Eman M Zaki, Sahar A El-Gammal, Noha G Sayed, Mayada F Sediek and Asmaa A Mohamed*

DOI : 10.32474/OAJOM.2019.02.000150

View abstract PDF Full text

Share

Introduction and Aim of the Work: CLL (Chronic lymphocytic leukemia) considered the most common type of leukemia in the western world and in Egypt CLL is the most common subtype of leukemias, the National Cancer Registry reported over 80% of lymphoid leukemias are CLL. This aim of the study was to investigate correlation between the overall survival, the disease free survival (DFS) of chronic lymphocytic leukemia (CLL) patients and the percentage of both (trisomy 12 detected by fluorescent in situ hybridization and CD49d expression by flow-cytometry) and in Chronic lymphocytic leukemia patients. Patients and Methods: Eighty patients from either sex, diagnosed as CLL patients, age of the patients ranged from 35 to 80 years old with mean of 61.55± 11.50 years, complete clinical and hematological profiles were done to them. CD49d tested ..... ReadMore

Lara Abdelmunim I Abdelrahman*, Mohamed E Gar Elanabi and Nahla Gafer

DOI : 10.32474/OAJOM.2019.02.000148

View abstract PDF Full text

Share

The study examined the association between Palliative radiotherapy and the improvement of the symptoms associated with metastatic breast cancer. These include metastatic in the spinal cord and associated pain, brain metes and associated symptoms, bone metes, Metastic in the lung and finally spread in organs such as liver and others. The study also dealt with the connection between it and the improvement of the standard of life of the patient and toxic and other important factors and was achieved through a set of international standards questionnaire by which the calibration of the result. The value of radiotherapy for palliation is well known to oncologists but not necessarily to other physicians. Using terms such as symptom improvement ratio (SIR) than traditional response rates might be more appropriate..... ReadMore

Lara Abdelmunim I Abdelrahman*, Mohamed E Gar Elanabi and Nahla gafer

DOI : 10.32474/OAJOM.2019.02.000147

View abstract PDF Full text

Share

Pain is one of the most common, unattended and unsolved problem for the cancer patients. Radiotherapy is successful, time efficient, well tolerated. The goal of palliative radiotherapy symptoms relief at the site of primary tumour or from metastic lesion. The study examined the association between Palliative radiotherapy and the improvement of the symptoms associated with metastatic breast cancer. These include metastatic in the spinal cord, bone and associated pain, also dealt with the connection between it and the improvement of the standard of life of the patient and toxic and other important factors and was achieved through a set of international standards questionnaire by which the calibration of the result. This study was conducted in the Center of tumours treatment in Sudan, represented in Khartoum oncology Hospi..... ReadMore

Victoria Aginova* and Natalia Dmitrieva

DOI : 10.32474/OAJOM.2019.02.000146

View abstract PDF Full text

Share

The emergence and spread of carbapenem-resistant (CarR) bacteria are a global problem for treatment of patients all over the world. This type of antimicrobial resistant is particularly danger by cancer patients. Regular monitoring of carbapenem-resistant microorganisms and the determination of the mechanism of their spread will help keep CarR bacteria from spreading This article contains the results of monitoring of carbapenem-resistant strains of microorganisms in the oncological clinic...... ReadMore

Tayyaba saher* and Muhammad Imran Qadir

DOI : 10.32474/OAJOM.2019.02.000145

View abstract PDF Full text

Share

The present study was objected to check the awareness about SARS among scholars of university. The pupil of Bahauddin Zakariya university Multan acted as the subjects for this research. Total of 109 subjects showed consent to be the part of this study. Severe acute respiratory syndrome (SARS) is considered a deadly animal virus which, perhaps originated from bats and then it was spread to other animals. According to a report, the humans were affected by SARS very firstly in 2002 in Guangdong, china...... ReadMore

Rüdiger Hardeland

DOI : 10.32474/OAJOM.2018.02.000144

View abstract PDF Full text

Share

The release of exosomes and ectosomes carrying noncoding RNAs is addressed in the context of cancer, with focus on microRNAs and long noncoding RNAs as well as differences in RNA cargos produced by tumor and nontumor cells. The differential appearance of ncRNAs can be used for diagnostic and prognostic purposes. Beyond these possibilities, the spreading of pathological and beneficial messages deserves particular attention and will gain future importance. Especially the use of exosomes released by cells that overexpress ncRNAs with antitumor properties appears to be a promising strategy...... ReadMore

Misra Jata Shankar

DOI : 10.32474/OAJOM.2018.02.000143

View abstract PDF Full text

Share

Carcinoma cervix is a major health problem faced by Indian women and though its incidence has declined in urban population in recent years but in the rural India where 70% of the people dwell, cervical cancer still remains on top [1]. It is mainly due to illiteracy and ignorance about the factors contributing to the development of cervical cancer...... ReadMore

VK Khanna*

DOI : 10.32474/OAJOM.2018.02.000142

View abstract PDF Full text

Share

Increasing the population and off them living styles effect on the surrounding environment leads to changes in climate with time. In the long run, the climatic change could affect agriculture in several ways such as quantity and quality of crops in terms of productivity, growth rates, photosynthesis and transpiration rates, moisture availability etc. Among the agricultural crops maize is also one of the most important food crops. Predictions suggest that worldwide climate change will reduce maize production this will coincide with a substantial increase in demand for maize due to rising populations. However, selection for climate change adaptation cultivar is difficult due to complex genotype by environment interactions. The broader use of traits from alien species and the m..... ReadMore

VK Khanna*

DOI : 10.32474/OAJOM.2018.02.000141

View abstract PDF Full text

Share

The impact of climate change on agriculture will be one of the major deciding factors influencing the future food security of mankind on earth. Agriculture is not only sensitive to climate change but, at the same time, is one of the major drivers for climate change. Understanding the weather changes over a period of time and adjusting the management practices towards achieving better harvest is a challenge to the growth of agricultural sector as a whole. The most imminent climatic changes in recent times is the increase in the atmospheric temperatures due to increased levels of greenhouse gases such as carbon dioxide (CO 2 ), methane (CH 4 ), ozone (O 3 ), nitrous oxide (N 2 O) and chloro fluoro carbons (CFCs)...... ReadMore

Bakulesh Khamar*

DOI : 10.32474/OAJOM.2018.02.000140

View abstract PDF Full text

Share

Checkpoint inhibitors have demonstrated efficacy in squamous NSCLC with tolerable toxicity profile. They are used as a monotherapy, in combination with chemotherapy or following chemo-radiotherapy as a first line, second line or consolidation therapy. As a first line, Pembrolizumab improves outcome (PFS) as a monotherapy in patients with PD-L1 expression of ≥ 50% (HR; 0.35). When used with chemotherapy, it improves PFS (HR; 0.56) irrespective of PD-L1 expression level. Nivolumab also improves PFS (HR; 0.62), when used as a second line for those progressing with chemotherapy. Durvalumab improves PFS (HR; 0.68) when used following chemo-radio therapy as a consolidation therapy...... ReadMore