Bacterial small RNAs (sRNAs) are important molecules that regulate the expression of certain genes, depending on the different
growth conditions of the cell and they are widely used by bacteria. sRNAs help the bacteria survive by being involved in many cellular
processes such as nutrient deficiency, mobility, pH adaptation and oxidative stress. Current studies have succeeded in elucidating
how sRNAs modulate the expression of different transcription factors. Thus, the integration of sRNA activity into comprehensive
regulatory networks has begun to take place. Regulatory networks include regulatory circuits that have characteristic functions. In
this review, the roles of some characterized sRNAs in regulatory networks and their effects on transcription factors are discussed.
Furthermore, we describe specific regulatory circuits containing base pairing sRNAs and their importance in global regulation.
Keywords: Small RNA; regulatory network; transcriptional regulator