Over the past years, defensive immunity has been recognized as having an important role as a front-line mechanism and as
an integral part of the adaptive immune response. Immunity in One Humped Camel (Camelus dromedarius) exposed too many
diseases are spleen-dependent. In this review, we discuss the general aspects of the gross anatomy of the spleen (both internal and
external), based on location, position, relation, blood supply and innervations of the organ. The micro-architecture of the camel
anatomy was discussed using eosin and hematoxylene stain and the cells visible in the aspect of normal tissue histology. The aim
of the write-up is to examine the anatomy of the different sections in the spleen of the one-humped camel (Camelus dromedaries).