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ISSN: 2644-1306

Theranostics of Respiratory & Skin Diseases

Research Article(ISSN: 2644-1306)

Clinical Evaluation of Herbal Active Enriched Shampoo in Anti Dandruff Treatment

Volume 1 - Issue 1

Sudhir Sawarkar1*, Vinay Deshmukh2, Sankar Jayaganesh1 and Ovureddiar Perumal1

  • Author Information Open or Close
    • 1Dabur Research & Development, International Business Development, United Arab Emirates
    • 2Sarkone Life sciences, United Arab Emirates

    *Corresponding author: Dr. Sudhir Sawarkar, Dabur Research & Development, International Business Development, Dubai, United Arab Emirates, P.O.Box. 6399

Received: May 26, 2018;   Published: June 07, 2018

DOI: 10.32474/TRSD.2018.01.000105

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Abstract

The human scalp is susceptible to microbial build-up if not thoroughly and frequently washed with the appropriate cleansing agents such as shampoos. Natural oils are presented in our scalp and it called as a sebum and it is a fuel/food for the dandruff-causing microbe. Malassezia feeds off these oils, breaking it down into by products, including oleic acid; formation of oleic acid is a starting/ kick point of dandruff. Approximately 50% people in the world sensitive to the oleic acid and affected by the dandruff. Overall clinical study results revealed that usage of tested anti-dandruff shampoo is effective and significantly reduce the dandruff fungi in scalp. Efficacy was analyzed with changes in the intensity of hair fall over 6 weeks from baseline to treatment visits using Visual Analogue Scale (VAS). The average response of Visual Analogue Scale for visit1 and visit 5 was 6.287 and 0.350 respectively. The average response/changes of Visual Analogue Scale score for Visit1 is 100.00 and Visit 2 having the score of 74.360; Visit 3 having the 47.924, Visit 4 having the score of 19.453 and Visit 5 was having the score of 5.567. It is concluded that there is statistically significant difference between the average response of Visual Analogue Score (VAS) between Visit 1 and Visit 5 which is indicative of remarkable improvement of dandruff over a period of 6 weeks. The tea tree oil in the formula act as a carrier to carry the actives in to the deeper part of the scalp; synergistic combination of natural and synthetic chemicals helps to control the dandruff. Overall study confirmed that the synergistic combination of synthetic anti-dandruff and natural ingredients plays a crucial role in control the anti-fungal, anti-inflammatory and local immune stimulatory actions.

Keywords: Dandruff; Lemon oil; Tea tree oil; Rosemary oil; Climbazole

Abstract| Introduction| Materials and Methods| Study Design| Statistical Analysis| Results| Discussion| Conclusion| Acknowledgement| References|

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