A new study has found out that our human skeletal system is also an endocrine organ which induces the hormone called
osteocalcin and then transforms it into the body’s blood. Hormone-osteocalcin interacts with other tissue and organ hormones to
reach an optimal goal for daily activity. The question is, how we can make more osteocalcin, there are two ways- physical activity
and proper nutrition.
The human bone was thought to be just a simple organ that is
a mineralized tissue to protect the body’s organs. Today’s studies
have demonstrated that bone acts as an endocrine organ, and then
involved in interaction to change communication with other tissues
in the body that was not understood before [1]. The body tissue or
organs each other interact through the blood of the hormones. We
know the bone is very much a live organ, and bone is one of the
participating network signals to other organs by bone to produce
their own Hormone-osteocalcin circulating in the body’s blood [2].
Hormone-osteocalcin plays a crucial role in bone remodeling that
enables our bone to grow and recover from injuries [1]. Osteocalcin
is signaling in the brainstem, thalamus, and hypothalamus through
the blood-brain barrier (BBB). Those areas are influencing various
neurotransmitters synthesis and signaling to increase serotonin
synthesis [3]. New discoveries have proved the bone mass reduction
may also be linked to the weakening of muscles and memory and
cognitive issues [3].
Ongoing research in this area suggests staying physically
active regularly, and then it stimulates your bone to make more
osteocalcin, which will have these beneficial effects on muscle and
brain [4]. Osteocalcin naturally declines at the beginning of women
at age 30 and men at age 50 [5]. We should reinforce the message to
the people to be active during adolescence and early adult years, and
this means they reach a higher peak bone mass, which will protect
them from age-related problems linked to osteocalcin decline [6].
These findings can support public health messages regarding the
importance of staying active through middle age and later life.
Epidemiological studies have shown that very active people tend
to have less cognitive decline with aging than a sedentary lifestyle.
Maintaining physical activity has long been known to have antiaging
properties. With time, we understand its related functions
could increase more awareness in public health intervention in the
future.
Restoring osteocalcin levels reverses age-related decline in
exercise capability. However, be aware of daily eating patterns to
increase serum osteocalcin levels. When we closely look at food
resources related to increased osteocalcin of nutrients in your
blood. The information is about healthy bone-supporting nutrients
that will play an important role in bone health [7]. The nutrients can
be found in various foods, especially dark, leafy green vegetables:
mustard greens, swiss chard, collard greens, spinach, broccoli,
brussels sprouts, green beans, prunes, kiwi fruit, soybean oil,
avocado, and green peas. We can also find animal food resources,
such as hard and soft cheese, egg yolk, ground beef, beef liver, pork
chops, chicken, goose, and fermented plant foods, such as Asian natto. All of the facts have proven to increased serum osteocalcin
levels. That is, focuses on balance to establish a maximum efficacy
nutrient to give your body extra protection and healthy lifestyle
behaviors can help you and your family stay a step ahead.