Gastroesophageal reflux disease is the result of persistent Gastroesophageal reflux associated with symptoms and/or
complications. It is the most prevalent esophageal pathology in pediatric population and it is one of the most common causes for
medical consultations. The identification of extra esophageal manifestations and associated alarm signals allows an appropriate
treatment, an early identification of esophageal mucosal injury and prevention of complications.