Objectives: To determine the frequency of various dengue virus serotypes circulating among dengue patients residing in
Rawalpindi and Islamabad during dengue epidemic 2016.
Methods: A cross-sectional descriptive study was carried out among dengue patients admitted in Holy Family Hospital that
was basically the teaching hospital affiliated with Rawalpindi Medical University. The data was collected during dengue epidemic
from July - September 2016 pertinent to demographics, various bleeding manifestations, dengue virus infections and hospital stay
through consecutive sampling. Independent sample t-test was applied to determine the gender and residence wise duration of fever.
However, difference in mean age of dengue patients with varied clinical manifestations was ascertained by ANOVA. The data was
analyzed by means of SPSS version 25.0 and Microsoft Excel 2010.
Results: Out of 1286 dengue patients enrolled in research, most (69.6%) were males. Mean age of study subjects was 35.7±
1.57 years and 70% were residents of Islamabad. About 65.9% had Dengue Fever (DF) while 31.5% and 2.6% were diagnosed with
Dengue Haemorrhagic Fever (DHF) and Dengue Shock Syndrome (DSS) respectively. Mean duration of fever among our patients
was 2.1 ± 0.73 days. However, residence wise and gender wise difference in mean duration of fever was found to be statistically
significant with P<0.02 and P<0.01 respectively. DEN-2 and DEN-3 maximally prevailed. However, IgM and IgG were positive among
52.3% and 48.3% dengue patients respectively.
Conclusion: Dengue virus is affecting the population of Pakistan continuously. All four types of dengue virus prevailed in our
population including mixed serotypes. DEN-2 and DEN-3 were determined to be the dominant circulating serotypes with higher
propensity among males.