Diagnosis and Management of Vaginal Endometriosis Involvement in Postmenopausal Woman. A Case report
Volume 2 - Issue 3
Baquedano Mainar L*, Herrero Serrano R, Espiau Romera A, Gabasa Gorgas L, Pallarés Arnal V, Benito Vielba M,
Ortega Marcilla S and Lamarca Ballesteros M
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- Department of Gynecology, Miguel Servet University Hospital, Zaragoza, Spain
*Corresponding author:
Laura Baquedano Mainar, Gynecology Department, Paseo Isabel La Catholica 1-3, 50009, Miguel Servet
University Hospital, Zaragoza, Spain
Received: March 01, 2019; Published: March 07, 2019
DOI: 10.32474/OAJRSD.2019.02.000138
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Abstract
Endometriosis is a pathology which affects up to 10% of the female population in reproductive age characterized by the
presence of actively functional endometrial ectopic tissue that suffers cyclical changes that are induced by the ovarian hormones,
which produces a chronic inflammatory reaction. This disease occurs during the reproductive years and is rarely diagnosed after
menopause.
Case Report: A 51 years old woman, who had had a unilateral laparoscopic adnexectomy due to an endometrioma one year
before, was admitted because of postmenopausal vaginal bleeding. The medical examination only showed two polypoid formations
of 1 and 3cm located on posterior vaginal fornix which presented with smooth cystic surface. A histological analysis was carried
out revealing an endometriotic nature. Despite the bleeding, the patient was asymptomatic, consequently a close monitoring was
adopted.
Discussion: Typically, endometriosis resolves after natural or iatrogenic menopause due to declining estrogen levels.
Nonetheless, case reports over the years have highlighted the incidence of recurrent postmenopausal endometriosis. Occurrence or
progression of postmenopausal endometriosis lesions could be related to extra-ovarian production of estrogen by endometriosis
lesions and adipose tissue, which becomes the major estrogen-producing tissue after menopause. Hormone therapy (HT) may
reactivate endometriosis and stimulate malignant transformation in women with a history of endometriosis.
The risk of malignant transformation of premenopausal endometriosis is around 1%. Furthermore, patients with endometriosis
have an increased risk of ovarian cancer and other malignancies. These transformations appear to be further elevated in patients who
take HT, although this issue is not fully elucidated. The evidence is currently insufficient to support a conclusion about the optimal
HT for women with endometriosis. Given the uncertain risks of initiating it, it is laborious to determine the best management.
Conclusión: Vaginal involvement is an atypical endometriosis location, especially in menopausal women, thus close surveillance
is necessary.
Keywords:Endometriosis; Menopause; Vaginal Diseases; Vaginal Bleeding
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