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ISSN: 2641-1644

Open Access Journal of Reproductive System and Sexual Disorders

Research Article(ISSN: 2641-1644)

Anomalies Associated with Gastroschisis and Omphalocele in Villa Clara, Cuba: a 30-year series from 1990 to 2019

Volume 3 - Issue 1

Noel Taboada Lugo1, Ana E. Algora Hernández1, Manuela Herrera Martínez1, Gisela Noche González1, María E de la Torre Santos1, Lorna González Herrera2, Eliecer Anoceto Armiñana3 and Ismary Oliva Machado1

  • Author Information Open or Close
    • 1Department of Medical Genetics, Villa Clara Medical University, Cuba
    • 2Department of Radiology, Villa Clara Medical University, Cuba
    • 3Department of Pathology, Villa Clara Medical University, Cuba

    *Corresponding author: Noel Taboada Lugo, Department of Medical Genetics, Villa Clara Medical University 18th Libertadoresst, Santa Clara city, Cuba.

Received:August 17, 2020;   Published: September 11, 2020

DOI: 10.32474/OAJRSD.2020.03.000151

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Abstract

Background: Gastroschisis and omphalocele are the most common anterior abdominal walldefects. The aims of our study were to describe the prevalence trends of congenital anterior abdominal wall defectsand to determine the frequency and type of associated congenital anomalies in gastroschisis and omphalocele cases.

Methods: A retrospective, observational study, with data obtained by theCuban Registries of Congenital Malformations; was conducted in the Cuban province of Villa Clara from 1990 to 2019.

Results: A total of 158 cases with anterior abdominal wall defect were identified, 93 of them (59%) with gastroschisis and 53 with omphalocele. There was an increasing trend in the prevalence rate of the anterior abdominal wall defects during the study timeframe, mainly in gastroschisis prevalence. The prevalence rate of gastroschisis (per 10,000 live births) during the study time frame was two fold those of omphalocele (4.8 and 2.7 respectively). The majority of GS cases did not have additional anomalies (80/93 [86%]). There was a statistically significant difference between the proportions of isolated and associated cases. (p= 2, 2E- 08). Omphalocele cases were more likely to be diagnosed with at least one other CD than those with GS (25/53 [47%] vs. 12/93 [13%].

Conclusions: Arisein anterior abdominal wall defects prevalence has been noted in recent decades in Villa Clara province. The present study revealed that omphalocele cases were more likely to have other congenital anomalies, predominantly in musculoskeletal and cardiovascular systems.

Keywords: Abdominal wall defects; Gastroschisis; Omphalocele; Anomalies; Cuba

Abstract| Introduction| Patients and Methods| Results| Discussion| Conflict of Interest Statement| Funding statement| Acknowledgement| Results|

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