Effect of Transcranial Magnetic Stimulation and Cranial Electrotherapy Stimulation on Heroin Craving Volume 5 - Issue 4

Mostafa Shaaban Kandil¹*, Wafik Said Bahnasy², Amr Adel Haiba³, Gamal Taha Shamma⁴ and El-Sayed Abdel Hamid Gad⁵

• ¹Assistant Lecturer of neuropsychiatry, Faculty of Medicine, Tanta University, Egypt
• ²Professor of Neuropsychiatry, Faculty of Medicine, Tanta University, Egypt
• ³Assistant Professor of Neuropsychiatry, Faculty of Medicine, Tanta University, Egypt
• ⁴Professor of Neuropsychiatry, Faculty of Medicine, Tanta University, Egypt
• ⁵Professor of Neuropsychiatry, Faculty of Medicine, Tanta University, Egypt

Received:August 03, 2021   Published:August 11, 2021

Corresponding author:Mostafa Shaaban Kandil, Assistant Lecturer of neuropsychiatry, Faculty of Medicine, Tanta University, Egypt

DOI: 10.32474/SJPBS.2021.05.000218

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Abstract

Background: Craving is a central aspect of Heroin addiction and is considered a main cause of relapse after period of abstinence. The objectives of this work were to assess the efficacy of transcranial magnetic stimulation (TMS) and cranial electrotherapy stimulation (CES) on craving of heroin use disorder.

Methods: This study was performed on 80 patients with heroin use disorder. Patients were randomized either to receive active TMS versus sham TMS or to receive active CES versus sham CES. Cue induced heroin craving was assessed subjectively by brief substance craving scale (BSCS) and objectively by electroencephalogram (EEG) over 1 and 3 months follow up.

Results: The mean age of participants was 24.8 years and all of them were male. The study showed significant reduction of BSCS score and reduction of beta wave power after application of 10 sessions TMS or CES with least values in active TMS group which indicate less craving.

Conclusion: TMS and CES are effective non-invasive treatment modalities for the acute reduction of heroin craving Keywords: Craving; Heroin; Addiction; TMS; CES; EEG; BSCS

Abstract| Introduction| Subjects and Methods| TMS Protocol| CES Protocol| Results| Discussion| Conclusion| Recommendations| Limitations| Declaration| Authors Contributions:| Acknowledgement| References|