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ISSN: 2637-4722

Progressing Aspects in Pediatrics and Neonatology

Mini review(ISSN: 2637-4724)

Ifosfamide Encephalopathy in A 4yr Old with Ewing’s Sarcoma

Volume 2 - Issue 2

Edwin Dias* and Anusha Dias

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    • Professor and Head, Department of Pediatrics, SIMS & RC, India

    *Corresponding author: Edwin Dias, Professor and Head, Department of Pediatrics, SIMS & RC, Mangalore, India

Received: February 01, 2018   Published: February 08, 2019

DOI: 10.32474/PAPN.2019.02.000133

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Ifosfamide encephalopathy is a fatal toxicity of Ifosfamide therapy. 13 cases have been reported till the year of 2018 worldwide in children and none among Ewing’s sarcoma cases. Here we are discussing a unique case of Ifosfamide encephalopathy during the course of treatment of Ewing’s sarcoma and was on Ifosfamide therapy and developed encephalopathy. Child improved symptomatically with MESNA and mannitol. Child was found to be normal on follow up and chemotherapy treatment was continued..

Keywords:Encephalopathy; Ewing’s Sarcoma; Ifosfamide; Mesna

Abstract| Background| Case Summary| Biopsy Diagnosis| Discussion| References|