Primary mucosal malignant melanoma of oral cavity is a rare malignancy arising from the melanocytes. Mucosal melanomas of
the head and neck comprise just over 1% of all melanomas and of these about 50% arise in the oral cavity. Oral mucosal melanomas
are therefore rare, representing about 0.5% of oral malignancies and less than 0.01% of all oral biopsies. It tends to metastasize
and locally invade tissues more than other malignant tumours of the oral cavity. It occurs commonly in the maxillary gingiva more
frequently on the palate and lesser often in the mandibular gingiva. Here, we present a case of a mucosal malignant melanoma
involving the maxillary bone along with the immunohistochemical profile of the neoplasm.
Abbreviations:WHO: World Health Organization; PET: Positron Emission Tomography; WLE: Wide Local Excision; MND:
Modified Neck Dissection; AJCC: American Joint Committee on Cancer; CTLs: Cytotoxic T lymphocytes