Adenoid Cystic Carcinoma of the Sinonasal Tract: Two Cases Report

Volume 5 - Issue 2

Mouna Bellakhdher, Maha Mejbri*, Wassim Kermani and Mohamed Abdelkefi

Received: August 24, 2020;   Published:September 10, 2020

DOI: 10.32474/SJO.2020.05.000206

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Abstract

Adenoid cystic carcinomas (ACC) of the sinonasal tract is a malignant neoplasm, characterized by slow and insidious growth. Thus, patients usually present in advanced stages. Clinical presentation is unspecific. Treatment is based on surgery followed by radiotherapy. Since the tumor spreads through perineural and hematological routes, delayed metastasis and local recurrence may occur several years after remission. In the present manuscript, we report the case of two patients who present with an ACC of the maxillary sinus diagnosed in an advanced stage. Orbital and cerebral involvement was objectified in one patient. Treatment consists in surgery. Post-operative radiotherapy was performed in one patient. He had a complete remission. Loco-regional recurrence occurred in the second patient. ACC is a particular entity among sinonasal cancers. Further studies are needed to define multimodal treatment including surgery, radiotherapy, and chemotherapy

Keywords: Adenoid cystic carcinoma; sinonasal tract; surgery, radiotherapy

Abstract| Introduction| Case Presentation| Discussion and Conclusion| Funding and Conflict of Interest| References|