During an action observation (AO) and action execution,
specific group of neural substrates are activated [1]. They provide
a neural mechanism for understanding the actions of others called
as Mirror neurons (MNs) [2]. They also carry out motor grounding,
motion ersatz, language and emotion appreciation [1] (Figure 1).
Figure 1: Mirror Neuron System (MNS).
Affect sharing
Mirror neurons discharge not only throughout the selfexperience of pain but also during the perception of another
people’s pain [3]. Neuroimaging studies carried out in humans
while experiencing as well as witnessing pain demonstrates activity
in their anterior cingulate cortex (ACC) [4]. The human cingulate cortex contains mirror neurons. These neurons are activated in
pain and are reactivated witnessing the pain of others [5,6].
Common neural mechanism for emotional contagion
Researchers found that during pain experience and observation,
the rat brain activates the neurons in anterior cingulate cortex (area
24) which are similar in location, cytoarchitecture, and connectivity
to the location of the human cingulate cortex [5]. Studies also
reveal that the animals no longer feel the pain of other animals if
the mirror neurons are not active [6]. These mirror neurons are the
common neural mechanism for emotional contagion in mammals,
elucidating the neural basis of human- rat intersubjectivity [5].
Studies on the neural basis for emotion sharing is the most
momentous step in understanding the mechanism of empathy. As
lack of empathy is a main feature in various psychiatric disorders,
such as in psychopaths. Indistinct knowledge about mirror neurons,
anterior cingulate cortex and their role in emotional contagion and
empathy will throw light on reconnoitring the etiology and newfangled therapeutic possibilities for such disorders.