Continuous or Intermittent? Which Regimen of Enteral
Nutrition is Better for Acute Stroke Patients? a Systematic
Review and Meta-Analysis
Volume 3 - Issue 3
Miranda Nava Gabriel1*, María Elena Ramírez Bernal2 and Maria Odette Martí Torres3
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- 1Head of the Neurology, Service of the Regional Military Specialty Hospital of Guadalajara, Mexico
- 2Internal Physician of the Regional Military Specialty Hospital of Guadalajara, Mexico
- 3Dentist and Specialist in Orthodontics and Maxillary Orthopedics, Autonomous University of the State of Mexico
*Corresponding author:
Miranda Nava Gabriel, Head of the Neurology, Service of the Regional Military Specialty Hospital of
Guadalajara, Mexico
Received: November 13, 2019; Published: November 21, 2019
DOI: 10.32474/OJNBD.2019.03.000164
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Abstract
Introduction: Sleep is defined as the natural, periodic and reversible decrease in perception of the external environment, with
the preservation of a certain degree of reactivity to the environment and autonomous functions. Sleep consists of 2 phases, REM
phase and NREM phase, these phases alternate at night in the form of five to six cycles; of which the NREM phase is 75% presented
and the REM by 25%.
Thertita mark: Caffeine is a readily available short-acting stimulant that has been shown to reduce some of the deficits
associated with sleep loss. With the rubber mark the absorption is carried out on the oral mucosa, which generates a greater
bioavailability of the active substance and an immediate mechanism of action. The effective response dose can range from 100 mg
to 200 mg and the effect arises from 6 min of administered the active substance. It is important to note that the dose of caffeine in
chewing gum is directly proportional to the effects on sleep inertia, as well as the duration and maintenance of them.
Discussion: Being able to analyze the mechanisms of action of caffeine on sleep inertia, helps us to make a comparison of
chewing gum with caffeine vs placebo (simple gum). Chewing generates for a short period of time the maintenance of performance
on simple and complex tasks and improves alertness, with caffeine these same effects look prolonged for longer.
Conclusion: Caffeinated gum is an effective therapeutic presentation on sleep inertia. The dosage for a positive response ranges
from 75 to 200 mg depending on the circumstances of sleep restriction. That is, thanks to the effects generated by chewing on the
state of alertness and cognition and the potentialization and duration of them by caffeine.
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