Rett sindrome is a severe neuro developmental disorder that is a leading cause of mental retardation in females, characterized
by an apparently normal psycho motor development through the first 6 months of life, followed by stagnation and growth regression
in different are as like motor, language and social skills; patients often exhibitautistic behaviors in the early stages. Other symptoms
include seizures, breathing problems when awake such as hyper ventilation, apnea, and swallowing air; ataxia and stereotypich
and movements. It is caused by mutations in the X-linked gene encodingmethyl-CpG-binding protein 2 (MECP2) [1,2]. One case is
presented with positive molecular study.
Keywords: Autism; Intellectual Disability; Rett Syndrome