Hyponatremia in Psychiatric Inpatients: A Native Pilot
Study
Volume 3 - Issue 2
Saeed Shoja Shafti*, Alireza Memarie, Masomeh Rezaiel and Masomeh Hamidi
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- Department of Psychiatry, University of Social Welfare and Rehabilitation Sciences (USWR), Razi Psychiatric Hospital, Iran
*Corresponding author:
Saeed Shoja Shafti, Full Professor of Psychiatry, University of Social Welfare and Rehabilitation Sciences
(USWR), Razi Psychiatric Hospital, Iran
Received: September 23, 2019; Published: October 03, 2019
DOI: 10.32474/OJNBD.2019.03.000157
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Abstract
Introduction: Hyponatremia is one of the most frequent ion and water disorders and severe hyponatremia is associated with
well-known clinical symptoms and manifestations. In the present assessment the incidence and clinical profile of hyponatremia
have been probed among a great sample of non-western psychiatric inpatients and compared with the available data in literature
regarding prevalence and other associated clinical characteristics.
Methods: All inpatients with idiopathic hyponatremia during the last sixty-four months had been included in the present study.
Clinical diagnosis, as well, was in essence based on ‘Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5)’.
Statistical significance had been defined as a p value ≤0.05.
Results: While the annual incidence of hyponatremia in current evaluation was around 0.01%, the annual incidence of mortality
due to hyponatremia was around 0.001%. It was significantly more prevalent among male psychiatric inpatients (p<0.04) and
patients with duration of illness in excess of one year (p<0.04). Furthermore, it was meaningfully more evident among schizophrenic
patients (p<0.007), in comparison with remaining primary psychiatric disorders. There was no significant relationship between
hyponatremia and symptomatic profile, or serum level of sodium and occurrence of seizure.
Conclusion: Hyponatremia was significantly more prevalent among male patients and cases with duration of illness in excess
of one year. Furthermore, it was meaningfully more evident among schizophrenic patients.
Keywords: Hyponatremia; Psychiatric disorders; Psychotropic drugs; Schizophrenia
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