Hyponatremia in Psychiatric Inpatients: A Native Pilot
Volume 3 - Issue 2
Saeed Shoja Shafti*, Alireza Memarie, Masomeh Rezaiel and Masomeh Hamidi
Open or Close
- Department of Psychiatry, University of Social Welfare and Rehabilitation Sciences (USWR), Razi Psychiatric Hospital, Iran
Saeed Shoja Shafti, Full Professor of Psychiatry, University of Social Welfare and Rehabilitation Sciences
(USWR), Razi Psychiatric Hospital, Iran
Received: September 23, 2019; Published: October 03, 2019
To view the Full Article Peer-reviewed Article PDF
Introduction: Hyponatremia is one of the most frequent ion and water disorders and severe hyponatremia is associated with
well-known clinical symptoms and manifestations. In the present assessment the incidence and clinical profile of hyponatremia
have been probed among a great sample of non-western psychiatric inpatients and compared with the available data in literature
regarding prevalence and other associated clinical characteristics.
Methods: All inpatients with idiopathic hyponatremia during the last sixty-four months had been included in the present study.
Clinical diagnosis, as well, was in essence based on ‘Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5)’.
Statistical significance had been defined as a p value ≤0.05.
Results: While the annual incidence of hyponatremia in current evaluation was around 0.01%, the annual incidence of mortality
due to hyponatremia was around 0.001%. It was significantly more prevalent among male psychiatric inpatients (p<0.04) and
patients with duration of illness in excess of one year (p<0.04). Furthermore, it was meaningfully more evident among schizophrenic
patients (p<0.007), in comparison with remaining primary psychiatric disorders. There was no significant relationship between
hyponatremia and symptomatic profile, or serum level of sodium and occurrence of seizure.
Conclusion: Hyponatremia was significantly more prevalent among male patients and cases with duration of illness in excess
of one year. Furthermore, it was meaningfully more evident among schizophrenic patients.
Keywords: Hyponatremia; Psychiatric disorders; Psychotropic drugs; Schizophrenia