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ISSN: 2637-6628

Online Journal of Neurology and Brain Disorders

Mini Review(ISSN: 2637-6628)

CSF-Mediated Damage in Multiple Sclerosis: More than a Hypothesis Volume 5 - Issue 4

Ermelinda De Meo1,2 * and Raffaello Bonacchi1,2

  • 1Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience IRCCS San Raffaele Scientific Institute, Italy
  • 2Vita-Salute San Raffaele University, Italy

Received:April 28, 2021   Published:May 10, 2021

Corresponding author: Ermelinda De Meo, Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience IRCCS San Raffaele Scientific Institute, Italy

DOI: 10.32474/OJNBD.2021.05.000218

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Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS), with a neurodegenerative component, representing a major cause of disability in young adults. Although etiopathogenetic mechanisms underlying MS are largely unknown, recent pathological and MRI studies raised the hypothesis of a cerebrospinal fluid (CSF)-mediated mechanism of CNS damage.

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