CSF-Mediated Damage in Multiple Sclerosis: More than a Hypothesis
Volume 5 - Issue 4
Ermelinda De Meo1,2 * and Raffaello Bonacchi1,2
- 1Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience IRCCS San Raffaele Scientific Institute, Italy
- 2Vita-Salute San Raffaele University, Italy
Received:April 28, 2021 Published:May 10, 2021
Corresponding author: Ermelinda De Meo, Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience IRCCS San Raffaele Scientific Institute, Italy
DOI: 10.32474/OJNBD.2021.05.000218
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Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS), with a neurodegenerative component, representing a major cause of disability in young adults. Although etiopathogenetic mechanisms underlying MS are largely unknown, recent pathological and MRI studies raised the hypothesis of a cerebrospinal fluid (CSF)-mediated mechanism of CNS damage.
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