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ISSN: 2641-1725

LOJ Medical Sciences

Case Report(ISSN: 2641-1725)

Ciprofloxacin-Induced Cervical Spinal Stenosis and Upper Limb Paresis Post-Typhoid Fever: A Case Report Volume 5 - Issue 5

Yasser Mohammed Hassanain Elsayed*

  • Critical Care Unit, Fraskour Central Hospital, Damietta Health Affairs, Egyptian Ministry of Health (MOH), Damietta, Egypt

Received: November 23, 2020   Published: January 27, 2021

*Corresponding author: Yasser Mohammed Hassanain Elsayed, Critical Care Unit, Fraskour Central Hospital, Damietta Health Affairs, Egyptian Ministry of Health (MOH), Damietta, Egypt


DOI: 10.32474/LOJMS.2021.05.000222

Abstract PDF

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Abstract

Rationale: Typhoid (enteric) fever is one of the most serious infections worldwide. Drug-induced diseases is a vital issue in toxicology and clinical medicine. Ciprofloxacin is a fluoroquinolone antibiotic can cause a serious or irreversible disabling side including tendon, bone, muscles, joints, nerves, and central nervous system problems. Patient concerns: A middle-aged married male patient presented to the physician outpatient clinic with a typhoid fever progress to severe neck pain and weakness of both upper extremities.

Diagnosis: Ciprofloxacin-induced bilateral upper limb paresis and cervical spinal stenosis. Interventions: Magnetic resonance imaging Electrocardiography, Widal test, and decompressive surgical neck repair.

Outcomes: The deterioration after decompressive surgical neck repair had happened. Quadriplegia was a major complication.

Lessons: This is the first case that reports these adverse drug reactions with oral ciprofloxacin. Oral ciprofloxacin can induce bilateral upper limb paresis and cervical spinal stenosis. The identification of drug-induced disease is a pivotal step in the diagnosis decision making of any medical problems.

Keywords: Ciprofloxacin; drug-induced; typhoid fever; bilateral upper limb paresis; cervical spinal stenosis

Abbreviations: ECG: Electrocardiogram; MRI: Magnetic resonance imaging; VR: Ventricular rate

Abstract| Introduction| Case Presentation| Discussion| Conclusions| Conflicts of Interest| Acknowledgment| References|

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