Ciprofloxacin-Induced Cervical Spinal Stenosis and Upper
Limb Paresis Post-Typhoid Fever: A Case Report
Volume 5 - Issue 5
Yasser Mohammed Hassanain Elsayed*
- Critical Care Unit, Fraskour Central Hospital, Damietta Health Affairs, Egyptian Ministry of Health (MOH), Damietta, Egypt
Received: November 23, 2020 Published: January 27, 2021
*Corresponding author: Yasser Mohammed Hassanain Elsayed, Critical Care Unit, Fraskour Central Hospital, Damietta Health Affairs, Egyptian Ministry of Health (MOH), Damietta, Egypt
DOI: 10.32474/LOJMS.2021.05.000222
Abstract
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Abstract
Rationale: Typhoid (enteric) fever is one of the most serious infections worldwide. Drug-induced diseases is a vital issue in toxicology and clinical medicine. Ciprofloxacin is a fluoroquinolone antibiotic can cause a serious or irreversible disabling side including tendon, bone, muscles, joints, nerves, and central nervous system problems. Patient concerns: A middle-aged married male patient presented to the physician outpatient clinic with a typhoid fever progress to severe neck pain and weakness of both upper extremities.
Diagnosis: Ciprofloxacin-induced bilateral upper limb paresis and cervical spinal stenosis. Interventions: Magnetic resonance imaging Electrocardiography, Widal test, and decompressive surgical neck repair.
Outcomes: The deterioration after decompressive surgical neck repair had happened. Quadriplegia was a major complication.
Lessons: This is the first case that reports these adverse drug reactions with oral ciprofloxacin. Oral ciprofloxacin can induce bilateral upper limb paresis and cervical spinal stenosis. The identification of drug-induced disease is a pivotal step in the diagnosis decision making of any medical problems.
Keywords: Ciprofloxacin; drug-induced; typhoid fever; bilateral upper limb paresis; cervical spinal stenosis
Abbreviations: ECG: Electrocardiogram; MRI: Magnetic resonance imaging; VR: Ventricular rate
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