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ISSN: 2637-4544

Interventions in Gynaecology and Women's Healthcare

Research Article(ISSN: 2637-4544)

A Clinico Pathological Correlation Study of Leiomyoma of Uterus-An Institutional Experience

Volume 3 - Issue 4

Kavya Kota* and Manchuru Aruna

  • Author Information Open or Close
    • Department of Obstetrics and Gynaecology, JJM Medical College, Davangere, Karnataka, India

    *Corresponding author:Kavya Kota, Department of Obstetrics and Gynaecology, JJM Medical College, Davangere, Karnataka, India

Received:July 29, 2019;   Published: August 05, 2019

DOI: 10.32474/IGWHC.2018.03.000167

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Abstract

Background: Leiomyoma of the uterus forms the most common type of benign tumour of the uterus and also most common pelvic tumour in women. The symptomatology continues to be variable. Surgery has for long been the main mode of therapy for the myomas. For women who wish to retain their uterus for future pregnancies or other reasons myomectomy is known. Recent trend has been towards non surgical approaches like GnRH hormone analogues or agonists, RU486 or selective uterine artery embolization, Laparoscopic cryoablation, radio frequency thermal ablation, MRGUS.

Objective: To analyse the clinico pathological spectrum in cases of Leiomyoma of the uterus in JJM Medical College to know the pattern of presentation, pathological co relation with type of fibroid and endometrial and ovarian changes. Materials and methods: A clinical study of 200 cases of fibroid uterus was made in Department of Obstetrics and Gynaecology, JJM Medical College, Davangere, from July 2016 to May 2019. The cases were selected by random allocation and detailed examination, clinical examination and investigations were made.

Results: Leiomyoma is the most common benign tumour of the uterus commonly found in women of childbearing age, in the third decade 55%. Most common mode of presentation is menstrual disturbances 76% amongst which menorrhagia was seen in 54% of cases, primary infertility was seen in 15% of patients, intramural fibroids are the most common variety accounting for 60%, endometrial pattern was proliferative in 66%, cystic ovaries were seen 8% of patients and adenomyosis in 16% indicating hyperestrogenism.

Conclusion: Leiomyoma is the most common benign tumour of the pelvis commonly affecting women of childbearing age, most common in 3rd decade, most common in multipara. Most common presentation of leiomyoma is menstrual disturbances. Intramural is the most common variety, proliferative and hyperplastic endometrium was commonly reported. The presence of proliferative endometrium, adenomyosis and cystic ovaries are all indicative of hyperestrogenic state associated with development of fibroids.

Keywords: Fibroid; Leiomyoma; Hyperestrogenism; GnRH hormone; Endometrium

Abstract| Introduction| Objective| Materials and Methods| Results| Discussion| Conclusion| References|