Received: June 26, 2018;   Published: July 02, 2018

DOI: 10.32474/DDIPIJ.2018.01.000124

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Abstract

Inability to early diagnosis is a major concern for the treatment of fatal disease like cancer. Early diagnosis and treatment enhances the scope of disease curability. The accurate identification, realtime monitoring and targeting the cancerous tissues in a precise manner hold the key for longer progression free survival of a patient. Among different diagnostic techniques, fluorescence based minimally invasive bio-imaging techniques are considered to be ideal to have clear understanding about the physiological processes of the infected tissues as well as to reduce physical and mental stress of a patient. Super-resolution fluorescence microscopy has improved the spatial optical resolution of biological molecules, living cells and tissues with the use of highly fluorescent inorganic semiconductor nanocrystals, also known as quantum dots (QDs), with sizes ranging from 2 nm to 15 nm [1]. These nanocrystals comprised of elements belong to groups II–VI (eg, CdSe and CdTe), groups III–V (eg, InP), groups IV–VI (eg, PbS and PbSe) [2].

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