The present work is based on a careful analysis of the literature in order to find out what the right type of exercise can be
recommended to the patient with COPD. Starting from the basic assumption that exercise is itself a biological therapy, we have
looked to molecules that are critically altered in these patients so as to constitute potential molecular markers. We have also seen if,
how, and how much the exercise is able to determine a modulation of the levels of these molecules in a functional sense to improve
the clinical condition of the patients.
Abbreviations: COPD: Chronic Obstructive Pulmonary Disease; GOLD: Global Strategy for the Diagnosis; ADL: Activity of Daily
Living; ROS: Reactive Oxygen Species