The Relationship between Oxidative Stress, Obesity and Type 2 Diabetes Volume 2 - Issue 3

Fatma Mnif¹*, Loukil F¹, Sahnoun R¹, Arous A², Messoud T² and Abid M¹

• ¹Department of Endocrinology, Hedi Chaker Hospital, Tunisia
• ²Pharmacological faculty of Monastir, Tunisia

Received: September 17, 2019   Published: October 03, 2019

Corresponding author: Fatma Mnif, Department of Endocrinology, Hedi Chaker Hospital, Tunisia

DOI: 10.32474/ADO.2019.02.000140

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Abstract

Obesity is an excess of fat in the body, resulting from an imbalance between daily caloric intake and energy expenses, it was recognized as a disease in 1997 by the World Health Organization (WHO). A classic view of its etiology lies in an inability to use lipids and a chronic inequality between anabolism and the catabolism that would be causal in weight gain. According to WHO, obesity has reached the proportions of a global epidemic (more than one in ten adults in the world is obese).

Keywords: Oxidative stress; Type 2 diabetes; Obesity; Insulin; Magnesium

Abbreviations: WHO: World Health Organization; BMI: Body Mass Index; DID: Insulin Dependent Diabetes; NIDDM: Non-Insulin Dependent Diabetes; ADO: Oral Antidiabetic; HbA1c: Glycated Hemoglobin; AOS: Activated oxygen species; ADN: Acide Désoxyribo Nucléique; AGE: Advanced Glycation Products; Co A: Co-enzyme A; ACC: Acétyl Co-enzyme A Carboxylase; AMPK: Adénosine Monophosphate Protein Kinase; HGPO: Hyperglycémie provoquée par voie rale; HPLC: High Performance Liquid Chromatography; CT: Cholestérol Total; TG: Triglycérides; HDL-C: Hight density lipoproteins cholesterol

Abstract| Introduction| Patients and Methods| Statistical Analyzes| Results| Discussion| References|