The Specific Role of Periodontal Disease in
Lung Cancer Pathogenesis
Volume 1 - Issue 2
Nikolaos Andreas Chrysanthakopoulos*
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- Department of Pathological Anatomy, University of Athens, Greece
*Corresponding author:
Nikolaos Andreas Chrysanthakopoulos, Department of Pathological Anatomy, University of Athens, Greece
Received: January 25, 2018; Published: February 01, 2018
DOI: 10.32474/MADOHC.2018.01.000108
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Abstract
It has been proposed that poor oral hygiene, especially in high
risk patients could be a predatory factor for respiratory diseases.
Oral cavity that coincides with trachea could be a natural gate
for colonization by respiratory pathogens. Dental plaque can be
colonized by those that have been inhaled from the oro pharynx
cavity to the upper airways and then can approach the lower
airway and adhere to the bronchial or alveolar epithelium [1,2].
Periodontal Disease (PD) has been associated with chronic lung
diseases, such as Chronic Obstructive Pulmonary Disease (COPD)
[3,4]. It has also been recorded that pulmonary function in COPD
patient’s decreases with increasing Clinical Attachment Loss (CAL),
and an association between poor oral hygiene and COPD was
recorded after controlling for potential confounders, such as gender,
age, smoking andsocio-economic level [5]. The mentioned findings
were in accordance with those that carried out from previous casecontrol
and prospective studies [6-10].
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