Oral Mucosal Immune Suppression, Tolerance and Silencing: A Mini-Review

Volume 1 - Issue 2

Michael AB Naafs*

Received: January 30, 2018;   Published: February 08, 2018

DOI: 10.32474/MADOHC.2018.01.000109

Full Text PDF

To view the Full Article   Peer-reviewed Article PDF

Abstract

The mucosal immune system spans the mucosal surfaces of the oro-pharyngeal cavity, gastrointestinal tract, respiratory tract, as well as the exocrine glands. In this mini-review the pathogenesis, pathophysiology of oral immunity, tolerance and resilence are discussed, with a special emphasis on the the oral microbiome in immune disorders.

Abbrevations: MALT: Mucosa-Associated Lymphoid Tissue; PPRs: Pattern Recognition Receptors; TLRs: Toll-Like Receptors; LPS: Lipopolysaccharides; PAMPs: Pathogen-Associated Molecular Patterns

Abstract| Introduction| Conclusion| References|