Cadasil, Migraine and Multiple Sclerosis (MS)-The Risk of Misdiagnosis, Case Report

Volume 2 - Issue 5

Piotr Bogucki¹*, Paulina Felczak, Teresa Wierzba-Bobrowicz²,Halina Sienkiewicz-Jarosz and Urszula Fiszer¹

Received: June 26, 2018;   Published: July 13, 2018

DOI: 10.32474/MADOHC.2018.02.000148

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Abstract

Diagnostic criteria for multiple sclerosis (MS) have been changing for years to enable easier and faster ways to confirm diagnosis especially during last decade. They lead to earlier treatment of patients with MS what gives higher likelihood to keep patients fit and capable of working. Dissemination in time (DIT) and in space (DIS) are general rules which are necessary to diagnose MS what was maintained in all diagnostic criteria, which have been published up till now[1]. Current criteria were published in 2017 and enable diagnosing MS even in patients, who earlier could not have MS diagnosed. This results from the facts that CSF oligoclonal bands present in patients with DIS without DIT are enough to MS diagnose[2]. Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leucoencephalopathy (CADASIL) is a disease of small vessels related to gene NOTCH3 mutations leading to symptoms of migraine with aura, recurrent ischaemic incidences, cognitive impairment and behavioural disturbance.

Introduction| Case report| Discussion| References|