Role of Vitamin C in Prevention and Management of Hyperuricemia: A Review Volume 4 - Issue 3

Ayan Chatterjee¹* and Kaushiki Ganguly²

• ¹Assistant Professor, Department of Physiology, Guru Nanak Institutions, Telangana
• ²Haldia, West Bengal

Received: March 17, 2021;   Published: March 30, 2021

Corresponding author: Ayan Chatterjee, Assistant Professor, Department of Physiology, Guru Nanak Institutions, Telangana, Hyderabad, India

DOI: 10.32474/CDVS.2021.04.000187

Fulltext PDF

To view the Full Article   Peer-reviewed Article PDF

Abstract

Uric acid, a waste product normally present in the blood which produce after the breakdown of purines. The condition when serum uric acid elevated [≥7mg/dl in male, ≥6mg/dl in female] is known as hyperuricemia. Elevated uric acid can form crystals in the joints that cause gout [1]. Hyperuricemia is the major cause of producing gout. About 85%-90% of people develop hyperuricemia because of under excretion of urate while its over production occurs in the body. Hyperuricemia is not the only cause of development of gout. Monosodium urate monohydrate crystals modulate in the joints in the presence of various nucleating agents like insoluble collagens, chondroitin sulfate, cartilage fragments and other crystals when the intra-articular fluid is dehydrated in low temperature [2]. Moreover, vitamin C is a water-soluble micro nutrient that has anti-oxidental properties to prevent the oxidative damage by free radicals and protect the tissues [3]. In previous different studies it has been shown that, vitamin C also have uricosuric effect. It has a potential effect in lowering serum uric acid level that is beneficial for hyperuricemic patients as well as for gout patient. Vitamin C lowers the serum uric acid level by increasing urinary excretion of uric acid [4]. In this backdrop the present study has been undertaken to assess the effect of Vitamin C on lowering serum uric acid level, so that whether vitamin C can be used in the treatment of hyperuricemia patient as well as gout patient or not.

Background| Materials and Methods| Findings and Discussions| Conclusion| References|