An important role in the processes of adaptation and masking in humans is playing also the immune system. The innate
immune system functions as an interpreter of tissue damage and provides a first line of defense, also translates the information
to other repair and defense systems in the body by stimulating angiogenesis, wound repair, and activating adaptive immunity. It is
appropriate to consider autophagy a means for programmed cell survival balancing and counter-regulating apoptosis. Autophagy
seems to have a dichotomous role in tumorigenesis and tumor progression.