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ISSN: 2644-1217

Open Access Journal of Complementary & Alternative Medicine

Research ArticleOpen Access

Phytochemical and Antioxidant Activities of Different Fractional Extracts of Alstonia scholaris Linn Volume 2 - Issue 3

Md Abdul Kaium Siddiki and Md Shahidul Islam*

  • Department of Pharmacy, University of Science and Technology Chittagong (USTC), Bangladesh

Received: May 13, 2020;   Published: May 26, 2020

*Corresponding author: Md Shahidul Islam, Department of Pharmacy, University of Science and Technology Chittagong (USTC), Chattogram, Bangladesh

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Alstonia scholaris Linn is popularly known as the “Chatim” or the Devil tree, which are used as a well-known remedy for the treatment of various types of disorders in the Ayurvedic, Homoeopathic and Folklore system of medicine in Bangladesh, India and many others countries. Alstonia scholaris is mainly used for the treatment of diarrhoea and malaria as a tonic, febrifuge, emmenagogue, anticholeric and vulnerary. Considering the medical importance and source of origin, the plant Alstonia scholaris has been subjected for fractionation with different solvents. The different fractions of ethanolic extract of Alstonia scholaris were evaluated for antioxidant activity as well as biological activity. Phytochemical properties of leaves of Alstonia scholaris were also investigated. The different solvent fractions showed the presence of tannins, glycosides, steroids, and alkaloids. The different fractions of ethanolic extract of Alstonia scholaris were evaluated for the total phenolic content, total flavonoid content, reducing power capacity, total antioxidant activity and DPPH radical scavenging activity. From the result on the various antioxidant activity tests, it was found that Dia-ion resin adsorbed fraction showed the highest value, followed by petroleum ether fraction, ethyl acetate fraction and chloroform fraction. Overall results of the antioxidant evaluation and various biological screening tests were found satisfactory and may encourage researcher to use this plant as a source of potent antioxidant food material as well as bioactive toxic compounds to be used in therapeutic drugs preparation.

Keywords: Phytochemistry; Antioxidant Activities; Alstonia scholaris; Chloroform

Abstract| Introduction Methods and Materials Process of Extraction Determination of Total Antioxidant Activity Determination of Dpph Radical Scavenging Activity Results & Discussion Total Flavonoid Content Reducing Power Capacity Content Total Antioxidant Activity DPPH Radical Scavenging Activity Conclusion References


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